All Outputs (6)

High-resolution and highly accelerated MRI T2 mapping as a tool to characterise renal tumour subtypes and grades (2024)
Journal Article
Horvat-Menih, I., Li, H., Priest, A. N., Li, S., Gill, A. B., Mendichovszky, I. A., Francis, S. T., Warren, A. Y., O’Carrigan, B., Welsh, S. J., Jones, J. O., Riddick, A. C. P., Armitage, J. N., Mitchell, T. J., Stewart, G. D., & Gallagher, F. A. (2024). High-resolution and highly accelerated MRI T2 mapping as a tool to characterise renal tumour subtypes and grades. European Radiology Experimental, 8(1), Article 76. https://doi.org/10.1186/s41747-024-00476-8

Background: Clinical imaging tools to probe aggressiveness of renal masses are lacking, and T2-weighted imaging as an integral part of magnetic resonance imaging protocol only provides qualitative information. We developed high-resolution and acceler... Read More about High-resolution and highly accelerated MRI T2 mapping as a tool to characterise renal tumour subtypes and grades.

DYNamic Assessment of Multi‐Organ level dysfunction in patients recovering from COVID‐19: DYNAMO COVID‐19 (2024)
Journal Article
Gupta, A., Nicholas, R., McGing, J. J., Nixon, A. V., Mallinson, J. E., McKeever, T. M., Bradley, C. R., Piasecki, M., Cox, E. F., Bonnington, J., Lord, J. M., Brightling, C. E., Evans, R. A., Hall, I. P., Francis, S. T., Greenhaff, P. L., & Bolton, C. E. (2024). DYNamic Assessment of Multi‐Organ level dysfunction in patients recovering from COVID‐19: DYNAMO COVID‐19. Experimental Physiology, 109(8), 1274-1291. https://doi.org/10.1113/ep091590

We evaluated the impacts of COVID-19 on multi-organ and metabolic function in patients following severe hospitalised infection compared to controls. Patients (n = 21) without previous diabetes, cardiovascular or cerebrovascular disease were recruited... Read More about DYNamic Assessment of Multi‐Organ level dysfunction in patients recovering from COVID‐19: DYNAMO COVID‐19.

Free-breathing Functional Pulmonary Proton MRI: A Novel Approach Using Voxel-wise Lung Ventilation (VOLVE) Assessment in Healthy Volunteers and Patients with Chronic Obstructive Pulmonary Disease (2024)
Journal Article
Peggs, Z. J., Brooke, J. P., Bolton, C. E., Hall, I. P., Francis, S. T., & Gowland, P. A. (2024). Free-breathing Functional Pulmonary Proton MRI: A Novel Approach Using Voxel-wise Lung Ventilation (VOLVE) Assessment in Healthy Volunteers and Patients with Chronic Obstructive Pulmonary Disease. Journal of Magnetic Resonance Imaging, https://doi.org/10.1002/jmri.29444

Background: In respiratory medicine, there is a need for sensitive measures of regional lung function that can be performed using standard imaging technology, without the need for inhaled or intravenous contrast agents. Purpose: To describe VOxel‐wis... Read More about Free-breathing Functional Pulmonary Proton MRI: A Novel Approach Using Voxel-wise Lung Ventilation (VOLVE) Assessment in Healthy Volunteers and Patients with Chronic Obstructive Pulmonary Disease.

Fast and High‐Resolution T2 Mapping Based on Echo Merging Plus k‐t Undersampling with Reduced Refocusing Flip Angles (TEMPURA) as Methods for Human Renal MRI (2024)
Journal Article
Li, H., Priest, A. N., Horvat‐Menih, I., Huang, Y., Li, S., Stewart, G. D., Mendichovszky, I. A., Francis, S. T., & Gallagher, F. A. (2024). Fast and High‐Resolution T2 Mapping Based on Echo Merging Plus k‐t Undersampling with Reduced Refocusing Flip Angles (TEMPURA) as Methods for Human Renal MRI. Magnetic Resonance in Medicine, 92(3), 1138-1148. https://doi.org/10.1002/mrm.30115

Purpose: To develop a highly accelerated multi‐echo spin‐echo method, TEMPURA, for reducing the acquisition time and/or increasing spatial resolution for kidney T2 mapping. Methods: TEMPURA merges several adjacent echoes into one k‐space by either co... Read More about Fast and High‐Resolution T2 Mapping Based on Echo Merging Plus k‐t Undersampling with Reduced Refocusing Flip Angles (TEMPURA) as Methods for Human Renal MRI.

Improvements in Between-Vendor MRI Harmonization of Renal T2 Mapping using Stimulated Echo Compensation (2024)
Journal Article
Li, H., Daniel, A. J., Buchanan, C. E., Nery, F., Morris, D. M., Li, S., Huang, Y., Sousa, J. A., Sourbron, S., Mendichovszky, I. A., Thomas, D. L., Priest, A. N., & Francis, S. T. (in press). Improvements in Between-Vendor MRI Harmonization of Renal T2 Mapping using Stimulated Echo Compensation. Journal of Magnetic Resonance Imaging, https://doi.org/10.1002/jmri.29282

Background: T2 mapping is valuable to evaluate pathophysiology in kidney disease. However, variations in T2 relaxation time measurements across MR scanners and vendors may occur requiring additional correction. Purpose: To harmonize renal T2 measurem... Read More about Improvements in Between-Vendor MRI Harmonization of Renal T2 Mapping using Stimulated Echo Compensation.

Assessment of Acute Kidney Injury using MRI (2024)
Journal Article
Selby, N. M., & Francis, S. T. (2024). Assessment of Acute Kidney Injury using MRI. Journal of Magnetic Resonance Imaging, https://doi.org/10.1002/jmri.29281

There has been growing interest in using quantitative magnetic resonance imaging (MRI) to describe and understand the pathophysiology of acute kidney injury (AKI). The ability to assess kidney blood flow, perfusion, oxygenation, and changes in tissue... Read More about Assessment of Acute Kidney Injury using MRI.