Role of EXO1 nuclease activity in genome maintenance, the immune response and tumor suppression in Exo1 D173A mice
(2022)
Journal Article
Wang, S., Lee, K., Gray, S., Zhang, Y., Tang, C., Morrish, R. B., …Chahwan, R. (2022). Role of EXO1 nuclease activity in genome maintenance, the immune response and tumor suppression in Exo1 D173A mice. Nucleic Acids Research, 50(14), 8093-8106. https://doi.org/10.1093/nar/gkac616
DNA damage response pathways rely extensively on nuclease activity to process DNA intermediates. Exonuclease 1 (EXO1) is a pleiotropic evolutionary conserved DNA exonuclease involved in various DNA repair pathways, replication, antibody diversificati... Read More about Role of EXO1 nuclease activity in genome maintenance, the immune response and tumor suppression in Exo1 D173A mice.