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All Outputs (30)

An elliptically symmetric angular Gaussian distribution (2017)
Journal Article
Paine, P., Preston, S. P., Tsagris, M., & Wood, A. T. (2018). An elliptically symmetric angular Gaussian distribution. Statistics and Computing, 28(3), 689-697. https://doi.org/10.1007/s11222-017-9756-4

We define a distribution on the unit sphere Sd−1 called the elliptically symmetric angular Gaussian distribution. This distribution, which to our knowledge has not been studied before, is a subfamily of the angular Gaussian distribution closely analo... Read More about An elliptically symmetric angular Gaussian distribution.

Bayesian model selection for the glacial-interglacial cycle (2017)
Journal Article
Carson, J., Crucifix, M., Preston, S., & Wilkinson, R. (2017). Bayesian model selection for the glacial-interglacial cycle. Journal of the Royal Statistical Society: Series C, 67(1), https://doi.org/10.1111/rssc.12222

A prevailing viewpoint in paleoclimate science is that a single paleoclimate record contains insufficient information to discriminate between typical competing explanatory models. Here we show that by using SMC 2 (sequential Monte Carlo squared) comb... Read More about Bayesian model selection for the glacial-interglacial cycle.

Event series prediction via non-homogeneous Poisson process modelling (2016)
Presentation / Conference Contribution
Goulding, J., Preston, S. P., & Smith, G. (2016). Event series prediction via non-homogeneous Poisson process modelling. In 2016 IEEE 16th International Conference on Data Mining (ICDM). https://doi.org/10.1109/ICDM.2016.0027

Data streams whose events occur at random arrival times rather than at the regular, tick-tock intervals of traditional time series are increasingly prevalent. Event series are continuous, irregular and often highly sparse, differing greatly in nature... Read More about Event series prediction via non-homogeneous Poisson process modelling.

Nonparametric hypothesis testing for equality of means on the simplex (2016)
Journal Article
Tsagris, M., Preston, S. P., & Wood, A. T. (in press). Nonparametric hypothesis testing for equality of means on the simplex. Journal of Statistical Computation and Simulation, 87(2), https://doi.org/10.1080/00949655.2016.1216554

In the context of data that lie on the simplex, we investigate use of empirical and exponential empirical likelihood, and Hotelling and James statistics, to test the null hypothesis of equal population means based on two independent samples. We perfo... Read More about Nonparametric hypothesis testing for equality of means on the simplex.

High-Resolution Three-Dimensional Structural Data Quantify the Impact of Photoinhibition on Long-Term Carbon Gain in Wheat Canopies in the Field (2015)
Journal Article
Burgess, A. J., Retkute, R., Pound, M. P., Foulkes, J., Preston, S. P., Jensen, O. E., …Murchie, E. H. (2015). High-Resolution Three-Dimensional Structural Data Quantify the Impact of Photoinhibition on Long-Term Carbon Gain in Wheat Canopies in the Field. Plant Physiology, 169(2), 1192-1204. https://doi.org/10.1104/pp.15.00722

Photoinhibition reduces photosynthetic productivity; however, it is difficult to quantify accurately in complex canopies partly because of a lack of high-resolution structural data on plant canopy architecture, which determines complex fluctuations o... Read More about High-Resolution Three-Dimensional Structural Data Quantify the Impact of Photoinhibition on Long-Term Carbon Gain in Wheat Canopies in the Field.

Piecewise Approximate Bayesian Computation: fast inference for discretely observed Markov models using a factorised posterior distribution (2013)
Journal Article
White, S. R., Kypraios, T., & Preston, S. P. (2015). Piecewise Approximate Bayesian Computation: fast inference for discretely observed Markov models using a factorised posterior distribution. Statistics and Computing, 25(2), 289-301. https://doi.org/10.1007/s11222-013-9432-2

© 2013, The Author(s). Many modern statistical applications involve inference for complicated stochastic models for which the likelihood function is difficult or even impossible to calculate, and hence conventional likelihood-based inferential techni... Read More about Piecewise Approximate Bayesian Computation: fast inference for discretely observed Markov models using a factorised posterior distribution.

Modelling the regulation of telomere length: the effects of telomerase and G-quadruplex stabilising drugs (2013)
Journal Article
Hirt, B. V., Wattis, J. A., & Preston, S. P. (2014). Modelling the regulation of telomere length: the effects of telomerase and G-quadruplex stabilising drugs. Journal of Mathematical Biology, 68(6), 1521-1552. https://doi.org/10.1007/s00285-013-0678-2

Telomeres are guanine-rich sequences at the end of chromosomes which shorten during each replication event and trigger cell cycle arrest and/or controlled death (apoptosis) when reaching a threshold length. The enzyme telomerase replenishes the ends... Read More about Modelling the regulation of telomere length: the effects of telomerase and G-quadruplex stabilising drugs.

The effects of a telomere destabilising agent on cancer cell-cycle dynamics - integrated modelling and experiments (2012)
Journal Article
Hirt, B. V., Wattis, J. A., Preston, S. P., & Laughton, C. A. (2012). The effects of a telomere destabilising agent on cancer cell-cycle dynamics - integrated modelling and experiments. Journal of Theoretical Biology, 295, https://doi.org/10.1016/j.jtbi.2011.10.038

The pentacyclic acridinium salt RHPS4 displays anti-tumour properties in vitro as well as in vivo and is potentially cell-cycle specific. We have collected experimental data and formulated a compartmental model using ordinary differential equations t... Read More about The effects of a telomere destabilising agent on cancer cell-cycle dynamics - integrated modelling and experiments.