Heterologous expression of a novel drug transporter from the malaria parasite alters resistance to quinoline antimalarials
(2018)
Journal Article
Tindall, S. M., Vallières, C., Lakhani, D. H., Islahudin, F., Ting, K.-N., & Avery, S. V. (in press). Heterologous expression of a novel drug transporter from the malaria parasite alters resistance to quinoline antimalarials. Scientific Reports, 8(1), https://doi.org/10.1038/s41598-018-20816-0
Antimalarial drug resistance hampers effective malaria treatment. Critical SNPs in a particular, putative amino acid transporter were recently linked to chloroquine (CQ) resistance in malaria parasites. Here, we show that this conserved protein (PF3D... Read More about Heterologous expression of a novel drug transporter from the malaria parasite alters resistance to quinoline antimalarials.