All Outputs (2)

Phenotypic heterogeneity is a selected trait in natural yeast populations subject to environmental stress (2013)
Journal Article
Holland, S. L., Reader, T., Dyer, P. S., & Avery, S. V. (2014). Phenotypic heterogeneity is a selected trait in natural yeast populations subject to environmental stress. Environmental Microbiology, 16(6), 1729-1740. https://doi.org/10.1111/1462-2920.12243

Populations of genetically uniform microorganisms exhibit phenotypic heterogeneity, where individual cells have varying phenotypes. Such phenotypes include fitness-determining traits. Phenotypic heterogeneity has been linked to increased population-l... Read More about Phenotypic heterogeneity is a selected trait in natural yeast populations subject to environmental stress.

Cell wall perturbation sensitizes fungi to the antimalarial drug chloroquine (2013)
Journal Article
Islahudin, F., Khozoie, C., Bates, S., Ting, K.-N., Pleass, R. J., & Avery, S. V. (2013). Cell wall perturbation sensitizes fungi to the antimalarial drug chloroquine. Antimicrobial Agents and Chemotherapy, 57(8), https://doi.org/10.1128/AAC.00478-13

Chloroquine (CQ) has been a mainstay of antimalarial drug treatment for several decades. Additional therapeutic actions of CQ have been described, including some reports of fungal inhibition. Here we investigated the action of CQ in fungi, including... Read More about Cell wall perturbation sensitizes fungi to the antimalarial drug chloroquine.