All Outputs (12)

Identifying neonatal transport research priorities: a modified Delphi consensus (2024)
Journal Article
Mistry, A., Leslie, A., Ojha, S., & Sharkey, D. (2024). Identifying neonatal transport research priorities: a modified Delphi consensus. Archives of Disease in Childhood. Fetal and Neonatal Edition, https://doi.org/10.1136/archdischild-2024-327213

Objectives: With increasing advances in neonatal transport, a focused research strategy is required to increase the evidence base towards providing optimal care. We aimed to identify the most important neonatal transport research questions as priorit... Read More about Identifying neonatal transport research priorities: a modified Delphi consensus.

Effects of implementation of a care bundle on rates of necrotising enterocolitis and own mother’s milk feeding in the East Midlands: protocol for a mixed methods impact and process evaluation study (2024)
Journal Article
Abramson, J., Szatkowski, L., Bains, M., Orton, E., Budge, H., Spruce, M., & Ojha, S. (2024). Effects of implementation of a care bundle on rates of necrotising enterocolitis and own mother’s milk feeding in the East Midlands: protocol for a mixed methods impact and process evaluation study. BMJ Open, 14(5), Article e078633. https://doi.org/10.1136/bmjopen-2023-078633

Introduction: Prevention of necrotising enterocolitis (NEC) is vital for improving neonatal outcomes. Feeding own mother’s milk helps prevent NEC. Rates of own mother’s milk feeding in the East Midlands are lower than the national average and the inc... Read More about Effects of implementation of a care bundle on rates of necrotising enterocolitis and own mother’s milk feeding in the East Midlands: protocol for a mixed methods impact and process evaluation study.

Impact of NICE clinical guidelines for prevention and treatment of neonatal infections on antibiotic use in very preterm infants in England and Wales: an interrupted time series analysis (2024)
Journal Article
Saunders, M., Ojha, S., & Szatkowski, L. (2024). Impact of NICE clinical guidelines for prevention and treatment of neonatal infections on antibiotic use in very preterm infants in England and Wales: an interrupted time series analysis. Archives of Disease in Childhood. Fetal and Neonatal Edition, https://doi.org/10.1136/archdischild-2024-326983

Objective: To assess the impact of publication of UK National Institute for Health and Care Excellence (NICE) guidelines on the prevention and treatment of early-onset infections (EOIs) in neonates (clinical guideline 149 (CG149), published in 2012,... Read More about Impact of NICE clinical guidelines for prevention and treatment of neonatal infections on antibiotic use in very preterm infants in England and Wales: an interrupted time series analysis.

A mixed-methods study to investigate feasibility and acceptability of an early warning score for preterm infants in neonatal units in Kenya: results of the NEWS-K study (2024)
Journal Article
Mitchell, E. J., Aluvaala, J., Bradshaw, L., Daniels, J. P., Emadau, C., Muthumbi, B., …Ojha, S. (2024). A mixed-methods study to investigate feasibility and acceptability of an early warning score for preterm infants in neonatal units in Kenya: results of the NEWS-K study. BMC Pediatrics, 24, Article 326. https://doi.org/10.1186/s12887-024-04778-z

Preterm birth (< 37 weeks gestation) complications are the leading cause of neonatal mortality. Early-warning scores (EWS) are charts where vital signs (e.g., temperature, heart rate, respiratory rate) are recorded, triggering action. To evaluate whe... Read More about A mixed-methods study to investigate feasibility and acceptability of an early warning score for preterm infants in neonatal units in Kenya: results of the NEWS-K study.

Association between opioid use during mechanical ventilation in preterm infants and evidence of brain injury: a propensity score-matched cohort study (2023)
Journal Article
Szatkowski, L., Sharkey, D., Budge, H., & Ojha, S. (2023). Association between opioid use during mechanical ventilation in preterm infants and evidence of brain injury: a propensity score-matched cohort study. eClinicalMedicine, 65, Article 102296. https://doi.org/10.1016/j.eclinm.2023.102296

Background: Preterm infants often require mechanical ventilation (MV), which can be a painful experience. Opioids (such as morphine) are used to provide analgesia, despite conflicting evidence about their impact on the developing brain. We aimed to q... Read More about Association between opioid use during mechanical ventilation in preterm infants and evidence of brain injury: a propensity score-matched cohort study.

Breastfeeding in infants diagnosed with Phenylketonuria (PKU): a scoping review (2023)
Journal Article
Kalvala, J., Chong, L., Chadborn, N., & Ojha, S. (2023). Breastfeeding in infants diagnosed with Phenylketonuria (PKU): a scoping review. BMJ Paediatrics Open, 7(1), Article e002066. https://doi.org/10.1136/bmjpo-2023-002066

Background: Phenylketonuria (PKU) is the most common inherited disease of amino acid metabolism, characterised by elevated levels of phenylalanine (Phe). There is a lack of infant feeding guidance for those with PKU. From birth to 6 months of age, br... Read More about Breastfeeding in infants diagnosed with Phenylketonuria (PKU): a scoping review.

How frequent is routine use of probiotics in UK neonatal units? (2023)
Journal Article
Patel, N., Evans, K., Berrington, J., Szatkowski, L., Costeloe, K., Ojha, S., …NeoTRIPS Collaborative Group. (2023). How frequent is routine use of probiotics in UK neonatal units?. BMJ Paediatrics Open, 7(1), Article e002012. https://doi.org/10.1136/bmjpo-2023-002012

Objective There is a lack of UK guidance regarding routine use of probiotics in preterm infants to prevent necrotising enterocolitis, late-onset sepsis and death. As practices can vary, we aimed to determine the current usage of probiotics within neo... Read More about How frequent is routine use of probiotics in UK neonatal units?.

Parents and healthcare professionals' attitudes to Kangaroo Care for preterm infants in the United Kingdom (2023)
Journal Article
Walker, S., Ojha, S., & Mitchell, E. J. (2023). Parents and healthcare professionals' attitudes to Kangaroo Care for preterm infants in the United Kingdom. Acta Paediatrica, https://doi.org/10.1111/apa.16795

Aim: To explore the attitudes of parents and healthcare professionals (HCPs), and facilitators and barrier to implementation of Kangaroo Care (KC) in the United Kingdom. Methods: Online cross-sectional survey; distributed via the British Association... Read More about Parents and healthcare professionals' attitudes to Kangaroo Care for preterm infants in the United Kingdom.

Observational cohort study of use of caffeine in preterm infants and association between early caffeine use and neonatal outcomes (2023)
Journal Article
Szatkowski, L., Fateh, S., Abramson, J., Kwok, T. C., Sharkey, D., Budge, H., & Ojha, S. (2023). Observational cohort study of use of caffeine in preterm infants and association between early caffeine use and neonatal outcomes. Archives of Disease in Childhood. Fetal and Neonatal Edition, 108(5), 505-510. https://doi.org/10.1136/archdischild-2022-324919

Objective: To quantify trends in caffeine use in infants born at

Sedation and analgesia from prolonged pain and stress during mechanical ventilation in preterm infants: is dexmedetomidine an alternative to current practice? (2022)
Journal Article
Ojha, S., Abramson, J., & Dorling, J. (2022). Sedation and analgesia from prolonged pain and stress during mechanical ventilation in preterm infants: is dexmedetomidine an alternative to current practice?. BMJ Paediatrics Open, 6(1), Article e001460. https://doi.org/10.1136/bmjpo-2022-001460

Mechanical ventilation is an uncomfortable and potentially painful intervention. Opioids, such as morphine and fentanyl, are used for analgesia and sedation but there is uncertainty whether they reduce pain in mechanically ventilated infants. Moreove... Read More about Sedation and analgesia from prolonged pain and stress during mechanical ventilation in preterm infants: is dexmedetomidine an alternative to current practice?.

Implementing two-stage consent pathway in neonatal trials (2021)
Journal Article
Mitchell, E., Oddie, S. J., Dorling, J., Gale, C., Johnson, M. J., McGuire, W., & Ojha, S. (2023). Implementing two-stage consent pathway in neonatal trials. Archives of Disease in Childhood. Fetal and Neonatal Edition, 108(1), F79-F82. https://doi.org/10.1136/archdischild-2021-322960

Perinatal trials sometimes require rapid recruitment processes to facilitate inclusion of participants when interventions are time-critical. A two-stage consent pathway has been used in some trials and is supported by national guidance. This pathway... Read More about Implementing two-stage consent pathway in neonatal trials.

Episiotomy and Initiation of Human Milk Feeds: A Retrospective Observational Study (2021)
Journal Article
Servante, J., Abramson, J., Walker, K. F., & Ojha, S. (2021). Episiotomy and Initiation of Human Milk Feeds: A Retrospective Observational Study. Breastfeeding Medicine, 16(5), 407-413. https://doi.org/10.1089/bfm.2020.0071

Objective: To investigate the association, in the United Kingdom, between having an episiotomy during childbirth and giving human milk by any modality as an infant's first feed. We also identified maternal demographic factors and perinatal experience... Read More about Episiotomy and Initiation of Human Milk Feeds: A Retrospective Observational Study.