All Outputs (2)

Human SETMAR is a DNA sequence-specific histone-methylase with a broad effect on the transcriptome (2018)
Journal Article
Tellier, M., & Chalmers, R. (2019). Human SETMAR is a DNA sequence-specific histone-methylase with a broad effect on the transcriptome. Nucleic Acids Research, 47(1), 122–133. https://doi.org/10.1093/nar/gky937

Transposons impart dynamism to the genomes they inhabit and their movements frequently rewire the control of nearby genes. Occasionally, their proteins are domesticated when they evolve a new function. SETMAR is a protein methylase with a sequence-sp... Read More about Human SETMAR is a DNA sequence-specific histone-methylase with a broad effect on the transcriptome.

Transposase subunit architecture and its relationship to genome size and the rate of transposition in prokaryotes and eukaryotes (2018)
Journal Article
Blundell-Hunter, G., Tellier, M., & Chalmers, R. (2018). Transposase subunit architecture and its relationship to genome size and the rate of transposition in prokaryotes and eukaryotes. Nucleic Acids Research, 46(18), 9637-9646. https://doi.org/10.1093/nar/gky794

Cut-and-paste transposons are important tools for mutagenesis, gene-delivery and DNA sequencing applications. At the molecular level, the most thoroughly understood are Tn5 and Tn10 in bacteria, and mariner and hAT elements in eukaryotes. All bacteri... Read More about Transposase subunit architecture and its relationship to genome size and the rate of transposition in prokaryotes and eukaryotes.