Therapeutic targeting of integrin ?v?6 in breast cancer

Moore, Kate M.; Thomas, Gareth J.; Duffy, Stephen W.; Warwick, Jane; Gabe, Rhian; Chou, Patrick; Ellis, Ian O.; Green, Andrew R.; Haider, Syed; Brouilette, Kellie; Saha, Antonio; Vallath, Sabari; Bowen, Rebecca; Chelala, Claude; Eccles, Diana; Tapper, William J.; Thompson, Alastair M.; Quinlan, Phillip; Jordan, Lee; Gillett, Cheryl; Brentnall, Adam; Violette, Shelia; Weinreb, Paul H.; Kendrew, Jane; Barry, Simon T.; Hart, Ian R.; Louise Jones, J.; Marshall, John F.

doi:10.1093/jnci/dju169

Background

Integrin αvβ6 promotes migration, invasion, and survival of cancer cells; however, the relevance and role of αvβ6 has yet to be elucidated in breast cancer.

Methods

Protein expression of integrin subunit beta6 (β6) was measured in... Read More about Therapeutic targeting of integrin ?v?6 in breast cancer.

All Outputs (1)