All Outputs (2)

Amelioration of mitochondrial dysfunction in heart failure through S-sulfhydration of Ca2+/calmodulin-dependent protein kinase II (2018)
Journal Article
Wu, D., Hu, Q., Tan, B., Rose, P., Zhu, D., & Zhu, Y. Z. (2018). Amelioration of mitochondrial dysfunction in heart failure through S-sulfhydration of Ca2+/calmodulin-dependent protein kinase II. Redox Biology, 19, 250-262. https://doi.org/10.1016/j.redox.2018.08.008

Aims: Ca2+/calmodulin-dependent protein kinase II (CaMKII) plays a critical role in the development of heart failure and in the induction of myocardial mitochondrial injury. Recent evidence has shown that hydrogen sulfide (H2S), produced by the enzym... Read More about Amelioration of mitochondrial dysfunction in heart failure through S-sulfhydration of Ca2+/calmodulin-dependent protein kinase II.

Garlic and gaseous mediators (2018)
Journal Article
Rose, P., Moore, P. K., & Zhu, Y.-Z. (in press). Garlic and gaseous mediators. Trends in Pharmacological Sciences, https://doi.org/10.1016/j.tips.2018.03.009

Garlic (Allium sativum) and allied plant species are rich sources of sulfur compounds. Major roles for garlic and its sulfur constituents include the regulation of vascular homeostasis and the control of metabolic systems linked to nutrient metabolis... Read More about Garlic and gaseous mediators.