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All Outputs (4)

In vitro anticancer properties and biological evaluation of novel natural alkaloid jerantinine B (2015)
Journal Article
Qazzaz, M. E., Raja, V. J., Lim, K.-H., Kam, T.-S., Lee, J. B., Gershkovich, P., & Bradshaw, T. D. (2016). In vitro anticancer properties and biological evaluation of novel natural alkaloid jerantinine B. Cancer Letters, 370(2), https://doi.org/10.1016/j.canlet.2015.10.013

Natural products play a pivotal role in medicine especially in the cancer arena. Many drugs that are currently used in cancer chemotherapy originated from or were inspired by nature. Jerantinine B (JB) is one of seven novel Aspidosperma indole alkalo... Read More about In vitro anticancer properties and biological evaluation of novel natural alkaloid jerantinine B.

Chain length affects pancreatic lipase activity and the extent and pH–time profile of triglyceride lipolysis (2015)
Journal Article
Benito-Gallo, P., Franceschetto, A., Wong, J. C., Marlow, M., Zann, V., Scholes, P., & Gershkovich, P. (2015). Chain length affects pancreatic lipase activity and the extent and pH–time profile of triglyceride lipolysis. European Journal of Pharmaceutics and Biopharmaceutics, 93, https://doi.org/10.1016/j.ejpb.2015.04.027

Triglycerides (TG) are one of the most common excipients used in oral lipid-based formulations. The chain length of the TG plays an important role in the oral bioavailability of the co-administered drug. Fatty acid (FA) chain-length specificity of po... Read More about Chain length affects pancreatic lipase activity and the extent and pH–time profile of triglyceride lipolysis.

Characterisation of human saliva as a platform for oral dissolution medium development (2015)
Journal Article
Gittings, S., Turnbull, N., Henry, B., Roberts, C. J., & Gershkovich, P. (2015). Characterisation of human saliva as a platform for oral dissolution medium development. European Journal of Pharmaceutics and Biopharmaceutics, 91, 16-24. https://doi.org/10.1016/j.ejpb.2015.01.007

Human saliva is a biological fluid of great importance in the field of dissolution testing. However, until now, no consensus has been reached on its key characteristics relevant to dissolution testing. As a result, it is difficult to select or develo... Read More about Characterisation of human saliva as a platform for oral dissolution medium development.