Flexible and rapid construction of viral chimeras applied to hepatitis C virus
(2016)
Journal Article
McClure, P. C., Urbanowicz, R. A., King, B. J., Cano-Crespo, S., Tarr, A. W., & Ball, J. K. (2016). Flexible and rapid construction of viral chimeras applied to hepatitis C virus. Journal of General Virology, 97(9), 2187-2193. https://doi.org/10.1099/jgv.0.000530
A novel and broadly applicable strategy combining site directed mutagenesis and DNA assembly for constructing seamless viral chimeras is described using Hepatitis C Virus as an exemplar. Full-length HCV genomic cloning cassettes, which contained flex... Read More about Flexible and rapid construction of viral chimeras applied to hepatitis C virus.