SPROUTY2 is a β-catenin and FOXO3a target gene indicative of poor prognosis in colon cancer
(2013)
Journal Article
Ordóñez-Morán, P., Irmisch, A., Barbáchano, A., Chicote, I., Tenbaum, S., Landolfi, S., …Pálmer, H. G. (2014). SPROUTY2 is a β-catenin and FOXO3a target gene indicative of poor prognosis in colon cancer. Oncogene, 33(15), 1975-1985. https://doi.org/10.1038/onc.2013.140
SPROUTY2 (SPRY2) is an intracellular regulator of receptor tyrosine kinase signaling involved in cell growth, differentiation and tumorigenesis. Here, we show that SPRY2 is a target gene of the Wnt/β-catenin pathway that is abnormally activated in mo... Read More about SPROUTY2 is a β-catenin and FOXO3a target gene indicative of poor prognosis in colon cancer.