All Outputs (2)

A signature motif mediating selective interactions of BCL11A with the NR2E/F subfamily of orphan nuclear receptors (2013)
Journal Article
Chan, C. M., Fulton, J., Montiel-Duarte, C., Collins, H. M., Bharti, N., Wadelin, F. R., …Heery, D. M. (2013). A signature motif mediating selective interactions of BCL11A with the NR2E/F subfamily of orphan nuclear receptors. Nucleic Acids Research, 41(21), https://doi.org/10.1093/nar/gkt761

Despite their physiological importance, selective interactions between nuclear receptors (NRs) and their cofactors are poorly understood. Here, we describe a novel signature motif (F/YSXXLXXL/Y) in the developmental regulator BCL11A that facilitates... Read More about A signature motif mediating selective interactions of BCL11A with the NR2E/F subfamily of orphan nuclear receptors.

Polycomb recruitment attenuates retinoic acid–induced transcription of the bivalent NR2F1 gene (2013)
Journal Article
Laursen, K. B., Mongan, N. P., Zhuang, Y., Ng, M. M., Benoit, Y. D., & Gudas, L. J. (2013). Polycomb recruitment attenuates retinoic acid–induced transcription of the bivalent NR2F1 gene. Nucleic Acids Research, 41(13), 6430–6443. https://doi.org/10.1093/nar/gkt367

Polycomb proteins play key roles in mediating epigenetic modifications that occur during cell differentiation. The Polycomb repressive complex 2 (PRC2) mediates the tri-methylation of histone H3 lysine 27 (H3K27me3). In this study, we identify a dist... Read More about Polycomb recruitment attenuates retinoic acid–induced transcription of the bivalent NR2F1 gene.