All Outputs (4)

Making Silicone Rubber Highly Resistant to Bacterial Attachment Using Thiol-ene Grafting (2016)
Journal Article
Magennis, E. P., Hook, A. L., Williams, P., & Alexander, M. R. (2016). Making Silicone Rubber Highly Resistant to Bacterial Attachment Using Thiol-ene Grafting. ACS Applied Materials and Interfaces, 8(45), 30780-30787. https://doi.org/10.1021/acsami.6b10986

Biomedical devices are indispensable in modern medicine yet offer surfaces that promote bacterial attachment and biofilm formation, resulting in acute and chronic healthcare-associated infections. We have developed a simple method to graft acrylates... Read More about Making Silicone Rubber Highly Resistant to Bacterial Attachment Using Thiol-ene Grafting.

The impact of surface chemistry modification on macrophage polarisation (2016)
Journal Article
Rostam, H., Singh, S., Salazar, F., Magennis, P., Hook, A. L., Singh, T., …Ghaemmaghami, A. M. (2016). The impact of surface chemistry modification on macrophage polarisation. Immunobiology, 221(11), 1237-1246. https://doi.org/10.1016/j.imbio.2016.06.010

Macrophages are innate immune cells that have a central role in combating infection and maintaining tissue homeostasis. They exhibit remarkable plasticity in response to environmental cues. At either end of a broad activation spectrum are pro-inflamm... Read More about The impact of surface chemistry modification on macrophage polarisation.

The influence of nanotexturing of poly(lactic-co-glycolic acid) films upon human ovarian cancer cell attachment (2016)
Journal Article
Yaşayan, G., Xue, X., Collier, P., Clarke, P., Alexander, M. R., & Marlow, M. (2016). The influence of nanotexturing of poly(lactic-co-glycolic acid) films upon human ovarian cancer cell attachment. Nanotechnology, 27(25), https://doi.org/10.1088/0957-4484/27/25/255102

In this study, we have produced nanotextured poly(lactic-co-glycolic acid) (PLGA) films by using polystyrene (PS) particles as a template to make a polydimethylsiloxane mould against which PLGA is solvent cast. Biocompatible, biodegradable and nanote... Read More about The influence of nanotexturing of poly(lactic-co-glycolic acid) films upon human ovarian cancer cell attachment.

Imaging of Crystalline and Amorphous Surface Regions Using Time-of-Flight Secondary-Ion Mass Spectrometry (ToF-SIMS): Application to Pharmaceutical Materials (2016)
Journal Article
Iuraş, A., Scurr, D. J., Boissier, C., Nicholas, M. L., Roberts, C. J., & Alexander, M. R. (2016). Imaging of Crystalline and Amorphous Surface Regions Using Time-of-Flight Secondary-Ion Mass Spectrometry (ToF-SIMS): Application to Pharmaceutical Materials. Analytical Chemistry, 88(7), 3481-3487. https://doi.org/10.1021/acs.analchem.5b02621

The structure of a material, in particular the extremes of crystalline and amorphous forms, significantly impacts material performance in numerous sectors such as semiconductors, energy storage, and pharmaceutical products, which are investigated in... Read More about Imaging of Crystalline and Amorphous Surface Regions Using Time-of-Flight Secondary-Ion Mass Spectrometry (ToF-SIMS): Application to Pharmaceutical Materials.