All Outputs (10)

Smoking, nicotine and pregnancy 2 (SNAP2) trial: protocol for a randomised controlled trial of an intervention to improve adherence to nicotine replacement therapy in pregnancy (2024)
Journal Article
Clark, M., Cooper, S., Naughton, F., Ussher, M., Emery, J., Mcdaid, L., …Coleman, T. (2024). Smoking, nicotine and pregnancy 2 (SNAP2) trial: protocol for a randomised controlled trial of an intervention to improve adherence to nicotine replacement therapy in pregnancy. BMJ Open, 14(5), Article e087175. https://doi.org/10.1136/bmjopen-2024-087175

Introduction: Smoking in pregnancy is harmful for unborn babies, infants, and women. Nicotine replacement therapy (NRT) is offered as usual stop smoking support in the UK. However, this is often used in insufficient doses, intermittently, or for too... Read More about Smoking, nicotine and pregnancy 2 (SNAP2) trial: protocol for a randomised controlled trial of an intervention to improve adherence to nicotine replacement therapy in pregnancy.

Smoking, nicotine and pregnancy 2 (SNAP2) trial: protocol for a randomised controlled trial of an intervention to improve adherence to nicotine replacement therapy during pregnancy (2024)
Journal Article
Clark, M. M., Cooper, S., Naughton, F., Ussher, M., Emery, J., McDaid, L., …Coleman, T. (2024). Smoking, nicotine and pregnancy 2 (SNAP2) trial: protocol for a randomised controlled trial of an intervention to improve adherence to nicotine replacement therapy during pregnancy. BMJ Open, 14(5), Article e087175. https://doi.org/10.1136/bmjopen-2024-087175

IntroductionSmoking during pregnancy is harmful to unborn babies, infants and women. Nicotine replacement therapy (NRT) is offered as the usual stop-smoking support in the UK. However, this is often used in insufficient doses, intermittently or for t... Read More about Smoking, nicotine and pregnancy 2 (SNAP2) trial: protocol for a randomised controlled trial of an intervention to improve adherence to nicotine replacement therapy during pregnancy.

The relationship between reported daily nicotine dose from NRT and daily cigarette consumption in pregnant women who smoke in an observational cohort study (2023)
Journal Article
Orton, S., Szatkowski, L., Naughton, F., Coleman, T., Clark, M., Cooper, S., …Thomson, R. (2024). The relationship between reported daily nicotine dose from NRT and daily cigarette consumption in pregnant women who smoke in an observational cohort study. Nicotine and Tobacco Research, 26(2), 212-219. https://doi.org/10.1093/ntr/ntad140

Introduction For non-pregnant people unable to quit smoking, the NHS recommends nicotine replacement therapy (NRT) for smoking reduction. This is not recommended during pregnancy due to concerns about higher nicotine intake than smoking alone. We inv... Read More about The relationship between reported daily nicotine dose from NRT and daily cigarette consumption in pregnant women who smoke in an observational cohort study.

Helping pregnant smokers quit: a multi-centre randomised controlled trial of electronic cigarettes versus nicotine replacement therapy (2023)
Journal Article
Przulj, D., Pesola, F., Myers Smith, K., McRobbie, H., Coleman, T., Lewis, S., …Hajek, P. (2023). Helping pregnant smokers quit: a multi-centre randomised controlled trial of electronic cigarettes versus nicotine replacement therapy. Health Technology Assessment, 27(13), https://doi.org/10.3310/AGTH6901

Background Some pregnant smokers try e-cigarettes, but effectiveness and safety of such use are unknown. Objectives To compare effectiveness and safety of nicotine patches and e-cigarettes in pregnancy. Design A pragmatic multi-centre random... Read More about Helping pregnant smokers quit: a multi-centre randomised controlled trial of electronic cigarettes versus nicotine replacement therapy.

Electronic cigarettes versus nicotine patches for smoking cessation in pregnancy: a randomized controlled trial (2022)
Journal Article
Hajek, P., Przulj, D., Pesola, F., Griffiths, C., Walton, R., McRobbie, H., …Myers Smith, K. (2022). Electronic cigarettes versus nicotine patches for smoking cessation in pregnancy: a randomized controlled trial. Nature Medicine, 28(5), 958-964. https://doi.org/10.1038/s41591-022-01808-0

Nicotine replacement therapy, in the form of nicotine patches, is commonly offered to pregnant women who smoke to help them to stop smoking, but this approach has limited efficacy in this population. Electronic cigarettes (e-cigarettes) are also used... Read More about Electronic cigarettes versus nicotine patches for smoking cessation in pregnancy: a randomized controlled trial.

Effectiveness of offering tailored text message, self‐help smoking cessation support to pregnant women who want information on stopping smoking: MiQuit3 randomised controlled trial (RCT) and meta‐analysis (2021)
Journal Article
Coleman, T., Clark, M., Welch, C., Whitemore, R., Leonardi‐Bee, J., Cooper, S., …Naughton, F. (2022). Effectiveness of offering tailored text message, self‐help smoking cessation support to pregnant women who want information on stopping smoking: MiQuit3 randomised controlled trial (RCT) and meta‐analysis. Addiction, 117(4), 1079-1094. https://doi.org/10.1111/add.15715

Aims: To test efficacy of “MiQuit’, a tailored, self-help, text message stop smoking programme for pregnancy, as an adjunct to usual care (UC) for smoking cessation in pregnancy. Design: Multicentre, open, two-arm, parallel-group, superiority rand... Read More about Effectiveness of offering tailored text message, self‐help smoking cessation support to pregnant women who want information on stopping smoking: MiQuit3 randomised controlled trial (RCT) and meta‐analysis.

A Qualitative Study of Factors Influencing Adherence among Pregnant Women Taking Part in a Trial of E-Cigarettes for Smoking Cessation (2021)
Journal Article
Ford, A., Uny, I., Lowes, J., Naughton, F., Cooper, S., Coleman, T., …Ussher, M. (2021). A Qualitative Study of Factors Influencing Adherence among Pregnant Women Taking Part in a Trial of E-Cigarettes for Smoking Cessation. International Journal of Environmental Research and Public Health, 18(2), Article 430. https://doi.org/10.3390/ijerph18020430

Use of e-cigarettes (vaping) has potential to help pregnant women stop smoking. This study explored factors influencing adherence among participants in the vaping arm of the first trial of vaping for smoking cessation in pregnancy. We conducted semi-... Read More about A Qualitative Study of Factors Influencing Adherence among Pregnant Women Taking Part in a Trial of E-Cigarettes for Smoking Cessation.

Examining the effectiveness of general practitioner and nurse promotion of electronic cigarettes versus standard care for smoking reduction and abstinence in hardcore smokers with smoking-related chronic disease: Protocol for a randomised controlled trial (2019)
Journal Article
Begh, R., Coleman, T., Yardley, L., Barnes, R., Naughton, F., Gilbert, H., …Aveyard, P. (2019). Examining the effectiveness of general practitioner and nurse promotion of electronic cigarettes versus standard care for smoking reduction and abstinence in hardcore smokers with smoking-related chronic disease: Protocol for a randomised controlled trial. Trials, 20(1), Article 659. https://doi.org/10.1186/s13063-019-3850-1

© 2019 The Author(s). Background: Despite the clear harm associated with smoking tobacco, many people with smoking-related chronic diseases or serious mental illnesses (SMI) are unwilling or unable to stop smoking. In many cases, these smokers have t... Read More about Examining the effectiveness of general practitioner and nurse promotion of electronic cigarettes versus standard care for smoking reduction and abstinence in hardcore smokers with smoking-related chronic disease: Protocol for a randomised controlled trial.

Autologous stem-cell transplantation in treatment-refractory Crohn's disease: an analysis of pooled data from the ASTIC trial (2017)
Journal Article

Background: The randomised controlled ASTIC trial showed no benefit of mobilisation and autologous haematopoietic stem-cell transplantation (HSCT) compared with mobilisation followed by conventional therapy using a stringent primary endpoint (steroid... Read More about Autologous stem-cell transplantation in treatment-refractory Crohn's disease: an analysis of pooled data from the ASTIC trial.

Autologous Hematopoetic Stem Cell Transplantation for Refractory Crohn Disease: A Randomized Clinical Trial (2015)
Journal Article

Importance: Case reports and series suggest hematopoietic stem cell transplantation (HSCT) may benefit some patients with Crohn disease. Objective: To evaluate the effect of autologous HSCT on refractory Crohn disease. Design, Setting, and Pa... Read More about Autologous Hematopoetic Stem Cell Transplantation for Refractory Crohn Disease: A Randomized Clinical Trial.