Novel detection of specific bacterial quorum sensing molecules in saliva: Potential non-invasive biomarkers for pulmonary Pseudomonas aeruginosa in cystic fibrosis

Webb, Karmel; Cámara, Miguel; Zain, Nur Masirah M.; Halliday, Nigel; Bruce, Kenneth D.; Nash, Edward F.; Whitehouse, Joanna L.; Knox, Alan; Forrester, Douglas; Smyth, Alan R.; Williams, Paul; Fogarty, Andrew; Barr, Helen L.

doi:10.1016/j.jcf.2021.08.030

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Novel detection of specific bacterial quorum sensing molecules in saliva: Potential non-invasive biomarkers for pulmonary Pseudomonas aeruginosa in cystic fibrosis (2021)
Journal Article
Webb, K., Cámara, M., Zain, N. M. M., Halliday, N., Bruce, K. D., Nash, E. F., …Barr, H. L. (2022). Novel detection of specific bacterial quorum sensing molecules in saliva: Potential non-invasive biomarkers for pulmonary Pseudomonas aeruginosa in cystic fibrosis. Journal of Cystic Fibrosis, 21(4), 626-629. https://doi.org/10.1016/j.jcf.2021.08.030

Pseudomonas aeruginosa produces specific signalling molecules, 2-alkyl-4-quinolones (AQs) that are detectable in the sputum of adults with cystic fibrosis (CF) and who have pulmonary infection with this opportunistic pathogen. This study aimed to det... Read More about Novel detection of specific bacterial quorum sensing molecules in saliva: Potential non-invasive biomarkers for pulmonary Pseudomonas aeruginosa in cystic fibrosis.