STAT1-cooperative DNA binding distinguishes type 1 from type 2 interferon signaling
(2014)
Journal Article
Begitt, A., Droescher, M., Meyer, T., Schmid, C. D., Baker, M., Antunes, F., …Vinkemeier, U. (in press). STAT1-cooperative DNA binding distinguishes type 1 from type 2 interferon signaling. Nature Immunology, 15(2), https://doi.org/10.1038/ni.2794
STAT1 is an indispensable component of a heterotrimer (ISGF3) and a STAT1 homodimer (GAF) that function as transcription regulators in type 1 and type 2 interferon signaling, respectively. To investigate the importance of STAT1-cooperative DNA bindin... Read More about STAT1-cooperative DNA binding distinguishes type 1 from type 2 interferon signaling.