Whole-body and adipose tissue-specific mechanisms underlying the metabolic effects of fibroblast growth factor 21 in the Siberian hamster

Lewis, Jo E.; Monnier, Chloe; Marshall, Hayley; Fowler, Maxine; Green, Rebecca; Cooper, Scott; Chiotellis, Aristeidis; Luckett, Jeni; Perkins, Alan C.; Coskun, Tamer; Adams, Andrew C.; Samms, Ricardo J.; Ebling, Francis J.P.; Tsintzas, Kostas

doi:10.1016/j.molmet.2019.10.009

All Outputs (1)

Whole-body and adipose tissue-specific mechanisms underlying the metabolic effects of fibroblast growth factor 21 in the Siberian hamster (2019)
Journal Article
Lewis, J. E., Monnier, C., Marshall, H., Fowler, M., Green, R., Cooper, S., …Tsintzas, K. (2020). Whole-body and adipose tissue-specific mechanisms underlying the metabolic effects of fibroblast growth factor 21 in the Siberian hamster. Molecular Metabolism, 31, 45-54. https://doi.org/10.1016/j.molmet.2019.10.009

Objective
Fibroblast growth factor 21 (FGF21) has been shown to rapidly lower body weight in the Siberian hamster, a preclinical model of adiposity. This induced negative energy balance mediated by FGF21 is associated with both lowered caloric intak... Read More about Whole-body and adipose tissue-specific mechanisms underlying the metabolic effects of fibroblast growth factor 21 in the Siberian hamster.