All Outputs (46)

Motor unit number estimates and neuromuscular transmission in the tibialis anterior of master athletes: evidence that athletic older people are not spared from age-related motor unit remodeling (2016)
Journal Article
Piasecki, M., Ireland, A., Coulson, J., Stashuk, D. W., Hamilton-Wright, A., Swiecicka, A., …Jones, D. A. (2016). Motor unit number estimates and neuromuscular transmission in the tibialis anterior of master athletes: evidence that athletic older people are not spared from age-related motor unit remodeling. Physiological Reports, 4(19), Article e12987. https://doi.org/10.14814/phy2.12987

Muscle motor unit numbers decrease markedly in old age, while remaining motor units are enlarged and can have reduced neuromuscular junction transmission stability. However, it is possible that regular intense physical activity throughout life can at... Read More about Motor unit number estimates and neuromuscular transmission in the tibialis anterior of master athletes: evidence that athletic older people are not spared from age-related motor unit remodeling.

A robust neuromuscular system protects rat and human skeletal muscle from sarcopenia (2016)
Journal Article
Pannérec, A., Springer, M., Migliavacca, E., Ireland, A., Piasecki, M., Karaz, S., …Feige, J. N. (2016). A robust neuromuscular system protects rat and human skeletal muscle from sarcopenia. Aging, 8(4), 712-728. https://doi.org/10.18632/aging.100926

Declining muscle mass and function is one of the main drivers of loss of independence in the elderly. Sarcopenia is associated with numerous cellular and endocrine perturbations, and it remains challenging to identify those changes that play a causal... Read More about A robust neuromuscular system protects rat and human skeletal muscle from sarcopenia.

Sex differences in the effects of 12 weeks sprint interval training on body fat mass and the rates of fatty acid oxidation and VO2max during exercise (2016)
Journal Article
Bagley, L., Slevin, M., Bradburn, S., Liu, D., Murgatroyd, C., Morrissey, G., …McPhee, J. S. (2016). Sex differences in the effects of 12 weeks sprint interval training on body fat mass and the rates of fatty acid oxidation and VO2max during exercise. BMJ Open Sport and Exercise Medicine, 2(1), Article e000056. https://doi.org/10.1136/bmjsem-2015-000056

Age-related neuromuscular changes affecting human vastus lateralis: age-related neuromuscular changes affecting human vastus lateralis (2015)
Journal Article
Piasecki, M., Ireland, A., Stashuk, D., Hamilton-Wright, A., Jones, D., & McPhee, J. (2016). Age-related neuromuscular changes affecting human vastus lateralis: age-related neuromuscular changes affecting human vastus lateralis. Journal of Physiology, 594(16), 4525-4536. https://doi.org/10.1113/jp271087

The anterior thigh muscles are particularly susceptible to muscle loss and weakness during ageing, although how this is associated with changes to neuromuscular structure and function in terms of motor unit (MU) number, size and MU potential (MUP) st... Read More about Age-related neuromuscular changes affecting human vastus lateralis: age-related neuromuscular changes affecting human vastus lateralis.

Age-dependent motor unit remodelling in human limb muscles (2015)
Journal Article
Piasecki, M., Ireland, A., Jones, D. A., & McPhee, J. S. (2016). Age-dependent motor unit remodelling in human limb muscles. Biogerontology, 17(3), 485-496. https://doi.org/10.1007/s10522-015-9627-3

Voluntary control of skeletal muscle enables humans to interact with and manipulate the environment. Lower muscle mass, weakness and poor coordination are common complaints in older age and reduce physical capabilities. Attention has focused on ways... Read More about Age-dependent motor unit remodelling in human limb muscles.

Nutritional status, body composition, and quality of life in community-dwelling sarcopenic and non-sarcopenic older adults: a case-control study (2015)
Journal Article
Verlaan, S., Aspray, T. J., Bauer, J. M., Cederholm, T., Hemsworth, J., Hill, T. R., …Brandt, K. (2017). Nutritional status, body composition, and quality of life in community-dwelling sarcopenic and non-sarcopenic older adults: a case-control study. Clinical Nutrition, 36(1), 267-274. https://doi.org/10.1016/j.clnu.2015.11.013

© 2015 The Authors Background & aim Sarcopenia, the age-related decrease in muscle mass, strength, and function, is a main cause of reduced mobility, increased falls, fractures and nursing home admissions. Cross-sectional and prospective studies indi... Read More about Nutritional status, body composition, and quality of life in community-dwelling sarcopenic and non-sarcopenic older adults: a case-control study.