All Outputs (43)

The 2022 symposium on dementia and brain aging in low‐ and middle‐income countries: Highlights on research, diagnosis, care, and impact (2024)
Journal Article
Kalaria, R., Maestre, G., Mahinrad, S., Acosta, D. M., Akinyemi, R. O., Alladi, S., Allegri, R. F., Arshad, F., Babalola, D. O., Baiyewu, O., Bak, T. H., Bellaj, T., Brodie‐Mends, D. K., Carrillo, M. C., Celestin, K., Damasceno, A., de Silva, R. K., de Silva, R., Djibuti, M., Dreyer, A. J., …Ismail, O. (2024). The 2022 symposium on dementia and brain aging in low‐ and middle‐income countries: Highlights on research, diagnosis, care, and impact. Alzheimer's & Dementia: The Journal of the Alzheimer's Association, https://doi.org/10.1002/alz.13836

Two of every three persons living with dementia reside in low‐ and middle‐income countries (LMICs). The projected increase in global dementia rates is expected to affect LMICs disproportionately. However, the majority of global dementia care costs oc... Read More about The 2022 symposium on dementia and brain aging in low‐ and middle‐income countries: Highlights on research, diagnosis, care, and impact.

EmpRess: an eHealth implementation readiness checklist for dementia developed through an interview study of stakeholder needs (2024)
Journal Article
Christie, H. L., Atefi, G., Craven, M. P., Orrell, M., & de Vugt, M. E. (2024). EmpRess: an eHealth implementation readiness checklist for dementia developed through an interview study of stakeholder needs. Aging and Mental Health, 28(5), 791-800. https://doi.org/10.1080/13607863.2024.2323951

Objective This study aimed to create a tool to assess eHealth interventions for dementia by adapting an existing implementation readiness (ImpRess) checklist that assessed manualised interventions. Methods In Part 1, online semi-structured inter... Read More about EmpRess: an eHealth implementation readiness checklist for dementia developed through an interview study of stakeholder needs.

Online peer support for people with Amyotrophic Lateral Sclerosis (ALS): a narrative synthesis systematic review (2024)
Journal Article
Gerritzen, E. V., Lee, A. R., McDermott, O., Coulson, N., & Orrell, M. (2024). Online peer support for people with Amyotrophic Lateral Sclerosis (ALS): a narrative synthesis systematic review. Frontiers in Digital Health, 6, Article 1138530. https://doi.org/10.3389/fdgth.2024.1138530

Background: Amyotrophic Lateral Sclerosis (ALS) significantly impacts the lives of people with the diagnosis and their families. A supportive social environment is important for people with ALS to adopt effective coping strategies and health behaviou... Read More about Online peer support for people with Amyotrophic Lateral Sclerosis (ALS): a narrative synthesis systematic review.

Promoting Activity, Independence, and Stability in Early Dementia and mild cognitive impairment (PrAISED): randomised controlled trial (2023)
Journal Article
Harwood, R. H., Goldberg, S. E., Brand, A., van Der Wardt, V., Booth, V., Di Lorito, C., Hoare, Z., Hancox, J., Bajwa, R., Burgon, C., Howe, L., Cowley, A., Bramley, T., Long, A., Lock, J., Tucker, R., Adams, E. J., O’Brien, R., Kearney, F., Kowalewska, K., …Masud, T. (2023). Promoting Activity, Independence, and Stability in Early Dementia and mild cognitive impairment (PrAISED): randomised controlled trial. BMJ, 382, Article e074787. https://doi.org/10.1136/bmj-2023-074787

Objective To determine the effectiveness of an exercise and functional activity therapy intervention in adults with early dementia or mild cognitive impairment compared with usual care. Design Randomised controlled trial. Setting Participants’... Read More about Promoting Activity, Independence, and Stability in Early Dementia and mild cognitive impairment (PrAISED): randomised controlled trial.

A predictive model of carer resilience in dementia family caregiving: A structural equation modelling approach (2023)
Journal Article
Leung, P., Orrell, M., Yates, L., & Orgeta, V. (2023). A predictive model of carer resilience in dementia family caregiving: A structural equation modelling approach. International Journal of Geriatric Psychiatry, 38(7), Article e5945. https://doi.org/10.1002/gps.5945

Objectives: This study aimed to investigate the mediating effects of quality of the caregiving relationship and other carer and person with dementia variables in predicting carer resilience over time. Method: Carers of people with mild and moderate d... Read More about A predictive model of carer resilience in dementia family caregiving: A structural equation modelling approach.

Community Occupational Therapy in Dementia intervention for people with mild to moderate dementia and their family carers in the UK: the VALID research programme including RCT (2023)
Journal Article
Wenborn, J., Mountain, G., Moniz-Cook, E., Poland, F., King, M., Omar, R., …Orrell, M. (2023). Community Occupational Therapy in Dementia intervention for people with mild to moderate dementia and their family carers in the UK: the VALID research programme including RCT. Programme Grants for Applied Research, 11(5), 1-76. https://doi.org/10.3310/rgtj7429

Background People with dementia find it increasingly difficult to carry out daily activities (activities of daily living), and may require increasing support from family carers. Researchers in the Netherlands developed the Community Occupational T... Read More about Community Occupational Therapy in Dementia intervention for people with mild to moderate dementia and their family carers in the UK: the VALID research programme including RCT.

Online peer support: views and experiences of people with young onset dementia (YOD) (2023)
Journal Article
Gerritzen, E. V., McDermott, O., & Orrell, M. (2023). Online peer support: views and experiences of people with young onset dementia (YOD). Aging and Mental Health, 27(12), 2386-2394. https://doi.org/10.1080/13607863.2023.2205833

Objectives: This study explores (1) which platforms people with YOD use for online peer support, (2) reasons for using or not using online peer support, and (3) how to optimise potential benefits and accessibility. Methods: A mixed-methods online sur... Read More about Online peer support: views and experiences of people with young onset dementia (YOD).

Dementia and hearing-aid use: a two-way street (2022)
Journal Article
Naylor, G., Dillard, L., Orrell, M., Stephan, B. C. M., Zobay, O., & Saunders, G. H. (2022). Dementia and hearing-aid use: a two-way street. Age and Ageing, 51(12), Article afac266. https://doi.org/10.1093/ageing/afac266

Objectives Hearing-aid use may reduce risk of dementia, but cognitive impairment makes use more challenging. An observed association between reduced hearing-aid use and incident dementia could reflect either or both of these causal paths. The object... Read More about Dementia and hearing-aid use: a two-way street.

A cross sectional survey on UK older adult’s attitudes to ageing, dementia and positive psychology attributes (2022)
Journal Article
Thelu, M., Webster, B., Jones, K., & Orrell, M. (2022). A cross sectional survey on UK older adult’s attitudes to ageing, dementia and positive psychology attributes. BMC Geriatrics, 22, Article 837. https://doi.org/10.1186/s12877-022-03539-w

Background With an increasingly ageing population worldwide, the predominant attitude towards ageing is still negative. Negative stereotypes have detrimental effects on individuals’ physical and mental health. Evidence is required about factors that... Read More about A cross sectional survey on UK older adult’s attitudes to ageing, dementia and positive psychology attributes.

A Self-management App for People Living With Mild Dementia (PRIDE): Protocol for a Pre-Post Feasibility Study (2022)
Journal Article
Lee, A. R., McDermott, O., Guo, B., Roe, J., & Orrell, M. (2022). A Self-management App for People Living With Mild Dementia (PRIDE): Protocol for a Pre-Post Feasibility Study. JMIR Research Protocols, 11(7), Article e33881. https://doi.org/10.2196/33881

Background: With the rapid increase in the prevalence of dementia in the United Kingdom and beyond, the emotional, social, and economic burden on individuals, families, and health care services continues to rise. Currently, interventions that enable... Read More about A Self-management App for People Living With Mild Dementia (PRIDE): Protocol for a Pre-Post Feasibility Study.

Dementia Early-Stage Cognitive Aids New Trial (DESCANT) of memory aids and guidance for people with dementia: randomised controlled trial (2021)
Journal Article
Clarkson, P., Pitts, R., Islam, S., Peconi, J., Russell, I., Fegan, G., …Robinson, C. (2022). Dementia Early-Stage Cognitive Aids New Trial (DESCANT) of memory aids and guidance for people with dementia: randomised controlled trial. Journal of Neurology, Neurosurgery and Psychiatry, 93(9), 1001-1009. https://doi.org/10.1136/jnnp-2021-326748

BACKGROUND: Common memory aids for people with dementia at home are recommended. However, rigorous evaluation is lacking, particularly what guidance or support is valued. OBJECTIVE: To investigate effects of memory aids and guidance by dementia suppo... Read More about Dementia Early-Stage Cognitive Aids New Trial (DESCANT) of memory aids and guidance for people with dementia: randomised controlled trial.

Anticholinergic drugs and risk of dementia: Time for action? (2021)
Journal Article
Bell, B., Avery, A., Bishara, D., Coupland, C., Ashcroft, D., & Orrell, M. (2021). Anticholinergic drugs and risk of dementia: Time for action?. Pharmacology Research and Perspectives, 9(3), Article e00793. https://doi.org/10.1002/prp2.793

Evidence suggests that the prescription of bladder anticholinergics is increasing. Recent studies have accentuated concerns about whether certain prescribed medications could increase risk of dementia, including anticholinergic drugs, and specificall... Read More about Anticholinergic drugs and risk of dementia: Time for action?.

Promoting independence in Dementia (Pride): A feasibility randomized controlled trial (2021)
Journal Article
Csipke, E., Shafayat, A., Sprange, K., Bradshaw, L., Montgomery, A. A., Ogollah, R., …Orrell, M. (2021). Promoting independence in Dementia (Pride): A feasibility randomized controlled trial. Clinical Interventions in Aging, 16, 363-378. https://doi.org/10.2147/CIA.S281139

© 2021 Csipke et al. Background: There is a need for interventions to foster and maintain independence for people with dementia to support community living, improve morale, and reduce stigma. We investigated a social intervention to promote living we... Read More about Promoting independence in Dementia (Pride): A feasibility randomized controlled trial.

Community Occupational Therapy for people with dementia and family carers (COTiD-UK) versus treatment as usual (Valuing Active Life in Dementia [VALID]) study: A single-blind, randomised controlled trial (2021)
Journal Article
Wenborn, J., O’Keeffe, A. G., Mountain, G., Moniz-Cook, E., King, M., Omar, R. Z., …Orrell, M. (2021). Community Occupational Therapy for people with dementia and family carers (COTiD-UK) versus treatment as usual (Valuing Active Life in Dementia [VALID]) study: A single-blind, randomised controlled trial. PLoS Medicine, 18(1), Article e1003433. https://doi.org/10.1371/journal.pmed.1003433

© 2021 Wenborn et al. This is an open access article distributed under the terms of the Creative Commons Attribution License, which permits unrestricted use, distribution, and reproduction in any medium, provided the original author and source are cr... Read More about Community Occupational Therapy for people with dementia and family carers (COTiD-UK) versus treatment as usual (Valuing Active Life in Dementia [VALID]) study: A single-blind, randomised controlled trial.

Community Occupational Therapy for people with dementia and family carers (COTiD-UK) versus treatment as usual (Valuing Active Life in Dementia [VALID]) study: a single-blind, randomised controlled trial (2021)
Journal Article
Wenborn, J., O'Keeffe, A. G., Mountain, G., Moniz-Cook, E., King, M., Omar, R. Z., …Orrell, M. (2021). Community Occupational Therapy for people with dementia and family carers (COTiD-UK) versus treatment as usual (Valuing Active Life in Dementia [VALID]) study: a single-blind, randomised controlled trial. PLoS Medicine, 18(1), Article e1003433. https://doi.org/10.5522/04/13084151

Background We aimed to estimate the clinical effectiveness of Community Occupational Therapy for people with dementia and family carers–UK version (Community Occupational Therapy in Dementia–UK version [COTiD-UK]) relative to treatment as usual (T... Read More about Community Occupational Therapy for people with dementia and family carers (COTiD-UK) versus treatment as usual (Valuing Active Life in Dementia [VALID]) study: a single-blind, randomised controlled trial.

Narrative inquiry on case studies of crisis in dementia (2020)
Journal Article
Bosco, A., Schneider, J., Coleston-Shields, D. M., & Orrell, M. (2020). Narrative inquiry on case studies of crisis in dementia. Quality in Ageing and Older Adults, 21(3), 181-191. https://doi.org/10.1108/QAOA-02-2020-0002

Purpose: This study aims to explore the coping styles that can be inferred from the discourse of dyads with dementia, and how these appear to impact on care management. Design/methodology/approach: This was a case study approach. Participants were re... Read More about Narrative inquiry on case studies of crisis in dementia.

Developing a model of best practice for teams managing crisis in people with dementia: a consensus approach (2020)
Journal Article
Yates, J., Stanyon, M., Challis, D., Coleston-Shields, D. M., Dening, T., Hoe, J., …Orrell, M. (2020). Developing a model of best practice for teams managing crisis in people with dementia: a consensus approach. BMC Psychiatry, 20(1), Article 505. https://doi.org/10.1186/s12888-020-02899-0

© 2020, The Author(s). Background: Teams delivering crisis resolution services for people with dementia and their carers provide short-term interventions to prevent admission to acute care settings. There is great variation in these services across t... Read More about Developing a model of best practice for teams managing crisis in people with dementia: a consensus approach.

AQUEDUCT Intervention for Crisis Team Quality and Effectiveness in Dementia: Protocol for a Feasibility Study (2020)
Journal Article
Broome, E. E., Coleston-Shields, D. M., Dening, T., Moniz-Cook, E., Poland, F., Stanyon, M., & Orrell, M. (2020). AQUEDUCT Intervention for Crisis Team Quality and Effectiveness in Dementia: Protocol for a Feasibility Study. JMIR Research Protocols, 9(10), Article e18971. https://doi.org/10.2196/18971

Background: Specialist community teams often support people with dementia who experience crisis. These teams may vary in composition and models of practice, which presents challenges when evaluating their effectiveness. A best practice model for deme... Read More about AQUEDUCT Intervention for Crisis Team Quality and Effectiveness in Dementia: Protocol for a Feasibility Study.

Involving the person with dementia in crisis planning: Focus groups with crisis intervention teams (2020)
Journal Article
Bosco, A., Schneider, J., Di Lorito, C., Broome, E., Coleston-Shields, D. M., & Orrell, M. (2020). Involving the person with dementia in crisis planning: Focus groups with crisis intervention teams. International Journal of Environmental Research and Public Health, 17(15), Article 5412. https://doi.org/10.3390/ijerph17155412

© 2020 by the authors. Licensee MDPI, Basel, Switzerland. Dementia leads to progressive critical situations that can escalate to a crisis episode if not adequately managed. A crisis may also resolve spontaneously, or not resolve after receiving profe... Read More about Involving the person with dementia in crisis planning: Focus groups with crisis intervention teams.

Field-testing an iCST touch-screen application with people with dementia and carers: a mixed method study (2020)
Journal Article
Rai, H. K., Griffiths, R., Yates, L., Schneider, J., & Orrell, M. (2021). Field-testing an iCST touch-screen application with people with dementia and carers: a mixed method study. Aging and Mental Health, 25(6), 1008-1018. https://doi.org/10.1080/13607863.2020.1783515

Objectives: To test the individual Cognitive Stimulation Therapy (iCST) application with people with dementia and carers in order to modify and refine the application, and improve its usability. In an iterative development process, two different prot... Read More about Field-testing an iCST touch-screen application with people with dementia and carers: a mixed method study.