Potential role for pyruvate kinase M2 in the regulation of murine cardiac glycolytic flux during in vivo chronic hypoxia
(2021)
Journal Article
Handzlik, M. K., Tooth, D. J., Constantin-Teodosiu, D., Greenhaff, P. L., & Cole, M. A. (2021). Potential role for pyruvate kinase M2 in the regulation of murine cardiac glycolytic flux during in vivo chronic hypoxia. Bioscience Reports, 41(6), Article BSR20203170. https://doi.org/10.1042/bsr20203170
Carbohydrate metabolism in heart failure shares similarities to that following hypoxic exposure, and is thought to maintain energy homeostasis in the face of reduced O2 availability. As part of these in vivo adaptations during sustained hypoxia, the... Read More about Potential role for pyruvate kinase M2 in the regulation of murine cardiac glycolytic flux during in vivo chronic hypoxia.