The Impact of Primary Renal Diagnosis on Prognosis and the Varying Predictive Power of Albuminuria in the NURTuRE-CKD Study
(2024)
Journal Article
McDonnell, T., Kalra, P. A., Vuilleumier, N., Cockwell, P., Wheeler, D. C., Fraser, S. D. S., Banks, R. E., & Taal, M. W. (in press). The Impact of Primary Renal Diagnosis on Prognosis and the Varying Predictive Power of Albuminuria in the NURTuRE-CKD Study. American Journal of Nephrology,
All Outputs (15)
Glucagon-like peptide-1 receptor agonists – new evidence of kidney and cardiovascular protection from the FLOW and SELECT trials (2024)
Journal Article
Taal, M. W., & Selby, N. M. (in press). Glucagon-like peptide-1 receptor agonists – new evidence of kidney and cardiovascular protection from the FLOW and SELECT trials. American Journal of Kidney Diseases,
Kidney Beam - a cost-effective digital intervention to improve mental health (2024)
Journal Article
Greenwood, S. A., Briggs, J., Walklin, C., Mangahis, E., Young, H. M., Castle, E. M., Billany, R. E., Asgari, E., Bhandari, S., Bishop, N., Bramham, K., Burton, J. O., Campbell, J., Chilcot, J., Cooper, N., Deelchand, V., Graham-Brown, M. P., Haggis, L., Hamilton, A., Jesky, M., …Macdonald, J. (2024). Kidney Beam - a cost-effective digital intervention to improve mental health. Kidney International Reports, https://doi.org/10.1016/j.ekir.2024.08.030Background: There is inequity in provision of physical rehabilitation services for people living with chronic kidney disease (CKD). The Kidney BEAM trial evaluated the clinical value and cost effectiveness of a physical activity digital health interv... Read More about Kidney Beam - a cost-effective digital intervention to improve mental health.
Optimizing kidney and cardiovascular protection in an era of multiple effective treatments (2024)
Journal Article
Taal, M. W. (2024). Optimizing kidney and cardiovascular protection in an era of multiple effective treatments. Current Opinion in Nephrology and Hypertension, https://doi.org/10.1097/MNH.0000000000001019Purpose of review After decades of relying on the control of hypertension and treatment with renin angiotensin system inhibitors as the only evidence-based interventions to slow the progression of chronic kidney disease (CKD), we have entered an era... Read More about Optimizing kidney and cardiovascular protection in an era of multiple effective treatments.
Accuracy of glomerular filtration rate estimation using creatinine and cystatin C for identifying and monitoring moderate chronic kidney disease: the eGFR-C study. (2024)
Journal Article
Lamb, E. J., Barratt, J., Brettell, E. A., Cockwell, P., Dalton, R. N., Deeks, J. J., Eaglestone, G., Pellatt-Higgins, T., Kalra, P. A., Khunti, K., Loud, F. C., Ottridge, R. S., Potter, A., Rowe, C., Scandrett, K., Sitch, A. J., Stevens, P. E., Sharpe, C. C., Shinkins, B., Smith, A., …Taal, M. W. (2024). Accuracy of glomerular filtration rate estimation using creatinine and cystatin C for identifying and monitoring moderate chronic kidney disease: the eGFR-C study. Health Technology Assessment, 28(35), 1-169. https://doi.org/10.3310/HYHN1078Background: Estimation of glomerular filtration rate using equations based on creatinine is widely used to manage chronic kidney disease. In the UK, the Chronic Kidney Disease Epidemiology Collaboration creatinine equation is recommended. Other publi... Read More about Accuracy of glomerular filtration rate estimation using creatinine and cystatin C for identifying and monitoring moderate chronic kidney disease: the eGFR-C study..
A note on performance metrics for the Kidney Failure Risk Equation (2024)
Journal Article
Ålund, O., Unwin, R., Challis, B., Kalra, P. A., Taal, M. W., Wheeler, D. C., Fraser, S. D. S., Cockwell, P., & Söderberg, M. (2024). A note on performance metrics for the Kidney Failure Risk Equation. Nephrology Dialysis Transplantation, 39(9), 1523-1525. https://doi.org/10.1093/ndt/gfae098
Discontinuation of anti-tumour necrosis factor alpha treatment owing to blood test abnormalities, and cost-effectiveness of alternate blood monitoring strategies (2024)
Journal Article
Abhishek, A., Stevenson, M. D., Nakafero, G., Grainge, M. J., Evans, I., Alabas, O., Card, T., Taal, M. W., Aithal, G. P., Fox, C. P., Mallen, C. D., van der Windt, D. A., Riley, R. D., Warren, R. B., & Williams, H. C. (2024). Discontinuation of anti-tumour necrosis factor alpha treatment owing to blood test abnormalities, and cost-effectiveness of alternate blood monitoring strategies. British Journal of Dermatology, 190(4), 559-564. https://doi.org/10.1093/bjd/ljad430Background: There is no evidence base to support the use of 6-monthly monitoring blood tests for the early detection of liver, blood and renal toxicity during established anti-tumour necrosis factor alpha (TNFα) treatment. Objectives: To evaluate the... Read More about Discontinuation of anti-tumour necrosis factor alpha treatment owing to blood test abnormalities, and cost-effectiveness of alternate blood monitoring strategies.
National Unified Renal Translational Research Enterprise: Idiopathic Nephrotic Syndrome (NURTuRE-INS) study (2024)
Journal Article
Colby, E., Hayward, S., Benavente, M., Robertson, F., Bierzynska, A., Osborne, A., Parmesar, K., Afzal, M., Chapman, T., Ullah, F., Davies, E., Nation, M., Cook, W., Johnson, T., Andag, U., Radresa, O., Skroblin, P., Bayerlova, M., Unwin, R., Vuilleumier, N., …Saleem, M. A. (2024). National Unified Renal Translational Research Enterprise: Idiopathic Nephrotic Syndrome (NURTuRE-INS) study. Clinical Kidney Journal, 17(8), Article sfae096. https://doi.org/10.1093/ckj/sfae096Background
Idiopathic Nephrotic Syndrome (INS) is a heterogenous disease and current classification is based on observational responses to therapies or kidney histology. The National Unified Renal Translational Research Enterprise (NURTuRE)-INS coho... Read More about National Unified Renal Translational Research Enterprise: Idiopathic Nephrotic Syndrome (NURTuRE-INS) study.
Prospective study of change in skin autofluorescence over time and mortality in people receiving hemodialysis (2024)
Journal Article
Viramontes-Hörner, D., Selby, N. M., & Taal, M. W. (2024). Prospective study of change in skin autofluorescence over time and mortality in people receiving hemodialysis. Kidney International Reports, 9(7), 2110-2116. https://doi.org/10.1016/j.ekir.2024.03.020Introduction: Elevated skin autofluorescence (SAF), a measure of tissue accumulation of advanced glycation end products (AGEs), is a strong predictor of all-cause and cardiovascular mortality in the hemodialysis population. However, prospective studi... Read More about Prospective study of change in skin autofluorescence over time and mortality in people receiving hemodialysis.
Regional variation of COVID-19 admissions, acute kidney injury and mortality in England - a national observational study using administrative data (2024)
Journal Article
Kolhe, N. V., Fluck, R. J., & Taal, M. W. (in press). Regional variation of COVID-19 admissions, acute kidney injury and mortality in England - a national observational study using administrative data. BMC Infectious Diseases, 24(1), Article 346. https://doi.org/10.1186/s12879-024-09210-6Background: This study explores regional variations in COVID-19 hospitalization rates, in-hospital mortality, and acute kidney injury (AKI) in England. We investigated the influence of population demographic characteristics, viral strain changes, and... Read More about Regional variation of COVID-19 admissions, acute kidney injury and mortality in England - a national observational study using administrative data.
Patient and health professional views on risk-stratified monitoring of immune-suppressing treatment in adults with inflammatory diseases (2024)
Journal Article
Fuller, A., Hancox, J., Williams, H. C., Card, T., Taal, M. W., Aithal, G. P., Fox, C. P., Mallen, C. D., Maxwell, J. R., Bingham, S., Vedhara, K., & Abhishek, A. (in press). Patient and health professional views on risk-stratified monitoring of immune-suppressing treatment in adults with inflammatory diseases. Rheumatology, Article keae175. https://doi.org/10.1093/rheumatology/keae175Objective
To explore the acceptability of an individualised risk-stratified approach to monitoring for target-organ toxicity in adult patients with immune-mediated inflammatory diseases established on immune-suppressing treatment(s).
Methods
Adu... Read More about Patient and health professional views on risk-stratified monitoring of immune-suppressing treatment in adults with inflammatory diseases.
Multivariate canonical correlation analysis identifies additional genetic variants for chronic kidney disease (2024)
Journal Article
Osborne, A. J., Bierzynska, A., Colby, E., Andag, U., Kalra, P. A., Radresa, O., …Campbell, C. (2024). Multivariate canonical correlation analysis identifies additional genetic variants for chronic kidney disease. npj Systems Biology and Applications, 10(1), Article 28. https://doi.org/10.1038/s41540-024-00350-8Chronic kidney diseases (CKD) have genetic associations with kidney function. Univariate genome-wide association studies (GWAS) have identified single nucleotide polymorphisms (SNPs) associated with estimated glomerular filtration rate (eGFR) and blo... Read More about Multivariate canonical correlation analysis identifies additional genetic variants for chronic kidney disease.
Associations With Baseline Blood Pressure Control in NURTuRE-CKD (2024)
Journal Article
Lucas, B. J., Cockwell, P., Fraser, S. D., Kalra, P. A., Wheeler, D. C., & Taal, M. W. (2024). Associations With Baseline Blood Pressure Control in NURTuRE-CKD. Kidney International Reports, 9(5), 1508-1512. https://doi.org/10.1016/j.ekir.2024.02.013
Risk-stratified monitoring for sulfasalazine toxicity: prognostic model development and validation (2024)
Journal Article
Abhishek, A., Grainge, M., Card, T., Williams, H. C., Taal, M. W., Aithal, G. P., …Riley, R. (2024). Risk-stratified monitoring for sulfasalazine toxicity: prognostic model development and validation. RMD Open, 10(1), Article e003980. https://doi.org/10.1136/rmdopen-2023-003980Background Sulfasalazine-induced cytopenia, nephrotoxicity and hepatotoxicity is uncommon during long-term treatment. Some guidelines recommend 3 monthly monitoring blood tests indefinitely during long-term treatment while others recommend stopping m... Read More about Risk-stratified monitoring for sulfasalazine toxicity: prognostic model development and validation.
The development and internal pilot trial of a digital physical activity and emotional well-being intervention (Kidney BEAM) for people with chronic kidney disease (2024)
Journal Article
Young, H. M. L., Castle, E. M., Briggs, J., Walklin, C., Billany, R. E., Asgari, E., …Greenwood, S. A. (2024). The development and internal pilot trial of a digital physical activity and emotional well-being intervention (Kidney BEAM) for people with chronic kidney disease. Scientific Reports, 14, Article 700. https://doi.org/10.1038/s41598-023-50507-4This trial assessed the feasibility and acceptability of Kidney BEAM, a physical activity and emotional well-being self-management digital health intervention (DHI) for people with chronic kidney disease (CKD), which offers live and on-demand physica... Read More about The development and internal pilot trial of a digital physical activity and emotional well-being intervention (Kidney BEAM) for people with chronic kidney disease.