Skip to main content

Research Repository

Advanced Search

All Outputs (62)

Exploring parents’ experiences, attitudes and understanding of gastro-oesophageal reflux in infants (2024)
Journal Article
McVicar, K., Szatkowski, L., Ojha, S., Tunster, S., & Bains, M. (2024). Exploring parents’ experiences, attitudes and understanding of gastro-oesophageal reflux in infants. PLoS ONE, 19(9), Article 0309081. https://doi.org/10.1371/journal.pone.0309081

Background
Gastro-oesophageal reflux (GOR) affects nearly half of infants. Parents play a crucial role in management but more understanding of their attitudes and experiences is needed to inform future education, support and research. This study aim... Read More about Exploring parents’ experiences, attitudes and understanding of gastro-oesophageal reflux in infants.

Evaluation of the impact of the COVID-19 pandemic on a smoking cessation service in Derbyshire: An interrupted time series analysis (2024)
Journal Article
Gleeson, H., Earnshaw, J., Craig, C., Hodson, C., & Szatkowski, L. (2024). Evaluation of the impact of the COVID-19 pandemic on a smoking cessation service in Derbyshire: An interrupted time series analysis. PLoS ONE, 19(6), Article e0303876. https://doi.org/10.1371/journal.pone.0303876

Background
Data published early in the COVID-19 pandemic suggested that smokers infected with SARS-CoV-2 were more likely to need hospital treatment or die than non-smokers, and thus this was seen as a motivator to encourage smokers to make a quit a... Read More about Evaluation of the impact of the COVID-19 pandemic on a smoking cessation service in Derbyshire: An interrupted time series analysis.

Effects of implementation of a care bundle on rates of necrotising enterocolitis and own mother’s milk feeding in the East Midlands: protocol for a mixed methods impact and process evaluation study (2024)
Journal Article
Abramson, J., Szatkowski, L., Bains, M., Orton, E., Budge, H., Spruce, M., & Ojha, S. (2024). Effects of implementation of a care bundle on rates of necrotising enterocolitis and own mother’s milk feeding in the East Midlands: protocol for a mixed methods impact and process evaluation study. BMJ Open, 14(5), Article e078633. https://doi.org/10.1136/bmjopen-2023-078633

Introduction: Prevention of necrotising enterocolitis (NEC) is vital for improving neonatal outcomes. Feeding own mother’s milk helps prevent NEC. Rates of own mother’s milk feeding in the East Midlands are lower than the national average and the inc... Read More about Effects of implementation of a care bundle on rates of necrotising enterocolitis and own mother’s milk feeding in the East Midlands: protocol for a mixed methods impact and process evaluation study.

Impact of NICE clinical guidelines for prevention and treatment of neonatal infections on antibiotic use in very preterm infants in England and Wales: an interrupted time series analysis (2024)
Journal Article
Saunders, M., Ojha, S., & Szatkowski, L. (2024). Impact of NICE clinical guidelines for prevention and treatment of neonatal infections on antibiotic use in very preterm infants in England and Wales: an interrupted time series analysis. Archives of Disease in Childhood. Fetal and Neonatal Edition, https://doi.org/10.1136/archdischild-2024-326983

Objective: To assess the impact of publication of UK National Institute for Health and Care Excellence (NICE) guidelines on the prevention and treatment of early-onset infections (EOIs) in neonates (clinical guideline 149 (CG149), published in 2012,... Read More about Impact of NICE clinical guidelines for prevention and treatment of neonatal infections on antibiotic use in very preterm infants in England and Wales: an interrupted time series analysis.

Association between women’s experience of domestic violence and childhood vaccination in West Africa: Cross-sectional analysis of Demographic and Health Survey data (2023)
Journal Article
Daramola, T., & Szatkowski, L. (2023). Association between women’s experience of domestic violence and childhood vaccination in West Africa: Cross-sectional analysis of Demographic and Health Survey data. PLoS ONE, 18(11), Article e0293900. https://doi.org/10.1371/journal.pone.0293900

Background: In 2021, 25 million children worldwide did not receive full basic childhood vaccinations, the highest figure in over a decade. There are large variations between countries in vaccination coverage. Globally, the lifetime prevalence of dome... Read More about Association between women’s experience of domestic violence and childhood vaccination in West Africa: Cross-sectional analysis of Demographic and Health Survey data.

Association between opioid use during mechanical ventilation in preterm infants and evidence of brain injury: a propensity score-matched cohort study (2023)
Journal Article
Szatkowski, L., Sharkey, D., Budge, H., & Ojha, S. (2023). Association between opioid use during mechanical ventilation in preterm infants and evidence of brain injury: a propensity score-matched cohort study. eClinicalMedicine, 65, Article 102296. https://doi.org/10.1016/j.eclinm.2023.102296

Background: Preterm infants often require mechanical ventilation (MV), which can be a painful experience. Opioids (such as morphine) are used to provide analgesia, despite conflicting evidence about their impact on the developing brain. We aimed to q... Read More about Association between opioid use during mechanical ventilation in preterm infants and evidence of brain injury: a propensity score-matched cohort study.

Respiratory management and outcomes in high-risk preterm infants with development of a population outcome dashboard (2023)
Journal Article
Kwok, T. C., Poulter, C., Algarni, S., Szatkowski, L., & Sharkey, D. (2023). Respiratory management and outcomes in high-risk preterm infants with development of a population outcome dashboard. Thorax, 78(12), 1215–1222. https://doi.org/10.1136/thorax-2023-220174

Introduction: Bronchopulmonary dysplasia (BPD) is associated with adverse long-term respiratory and neurodevelopmental outcomes. No recent studies examined the changing respiratory management and outcomes, particularly severe BPD, across a whole popu... Read More about Respiratory management and outcomes in high-risk preterm infants with development of a population outcome dashboard.

Impact of postnatal dexamethasone timing on preterm mortality and bronchopulmonary dysplasia: a propensity score analysis (2023)
Journal Article
Kwok, T. C., Szatkowski, L., & Sharkey, D. (2023). Impact of postnatal dexamethasone timing on preterm mortality and bronchopulmonary dysplasia: a propensity score analysis. European Respiratory Journal, 62(4), Article 2300825. https://doi.org/10.1183/13993003.00825-2023

Introduction Postnatal dexamethasone (PND) is used in high-risk preterm infants after the first week of life to facilitate extubation and prevent bronchopulmonary dysplasia (BPD) but the optimal treatment timing remains unclear.

Objective Explore... Read More about Impact of postnatal dexamethasone timing on preterm mortality and bronchopulmonary dysplasia: a propensity score analysis.

The relationship between reported daily nicotine dose from NRT and daily cigarette consumption in pregnant women who smoke in an observational cohort study (2023)
Journal Article
Orton, S., Szatkowski, L., Naughton, F., Coleman, T., Clark, M., Cooper, S., …Thomson, R. (2024). The relationship between reported daily nicotine dose from NRT and daily cigarette consumption in pregnant women who smoke in an observational cohort study. Nicotine and Tobacco Research, 26(2), 212-219. https://doi.org/10.1093/ntr/ntad140

Introduction For non-pregnant people unable to quit smoking, the NHS recommends nicotine replacement therapy (NRT) for smoking reduction. This is not recommended during pregnancy due to concerns about higher nicotine intake than smoking alone. We inv... Read More about The relationship between reported daily nicotine dose from NRT and daily cigarette consumption in pregnant women who smoke in an observational cohort study.

How frequent is routine use of probiotics in UK neonatal units? (2023)
Journal Article
Patel, N., Evans, K., Berrington, J., Szatkowski, L., Costeloe, K., Ojha, S., …NeoTRIPS Collaborative Group. (2023). How frequent is routine use of probiotics in UK neonatal units?. BMJ Paediatrics Open, 7(1), Article e002012. https://doi.org/10.1136/bmjpo-2023-002012

Objective There is a lack of UK guidance regarding routine use of probiotics in preterm infants to prevent necrotising enterocolitis, late-onset sepsis and death. As practices can vary, we aimed to determine the current usage of probiotics within neo... Read More about How frequent is routine use of probiotics in UK neonatal units?.

Psychosocial Impacts of Infertility among Omani Women with Polycystic Ovarian Syndrome: A Qualitative Study (2023)
Journal Article
ALSumri, H., Szatkowski, L., Gibson, J., Fiaschi, L., & Bains, M. (2023). Psychosocial Impacts of Infertility among Omani Women with Polycystic Ovarian Syndrome: A Qualitative Study. International Journal of Fertility & Sterility, 17(2), 107-114. https://doi.org/10.22074/IJFS.2022.550111.1310

Background: To understand the psychosocial experience of infertility among women with polycystic ovarian syndrome in Oman.

Materials and Methods: In this qualitative study, semi-structured interviews were conducted with 20 Omani women diagnosed w... Read More about Psychosocial Impacts of Infertility among Omani Women with Polycystic Ovarian Syndrome: A Qualitative Study.

Observational cohort study of use of caffeine in preterm infants and association between early caffeine use and neonatal outcomes (2023)
Journal Article
Szatkowski, L., Fateh, S., Abramson, J., Kwok, T. C., Sharkey, D., Budge, H., & Ojha, S. (2023). Observational cohort study of use of caffeine in preterm infants and association between early caffeine use and neonatal outcomes. Archives of Disease in Childhood. Fetal and Neonatal Edition, 108(5), 505-510. https://doi.org/10.1136/archdischild-2022-324919

Objective: To quantify trends in caffeine use in infants born at <32 weeks' gestational age (GA), and to investigate the effects of early vs late caffeine on neonatal outcomes. Study design: Retrospective propensity score matched cohort study using r...

Association between polycystic ovarian syndrome and adverse pregnancy and neonatal outcomes among women in Oman (2022)
Journal Article
Alsumri, H., Fiaschi, L., Gibson, J., Bains, M., & Szatkowski, L. (2022). Association between polycystic ovarian syndrome and adverse pregnancy and neonatal outcomes among women in Oman. Journal of Health and Medical Informatics, 13, Article 54

Objectives: To examine the association between PCOS and selected metabolic, pregnancy and neonatal outcomes among pregnant women and their newborns. Methods: Cohort study using electronic hospital records from two tertiary hospitals in Oman. Data wer... Read More about Association between polycystic ovarian syndrome and adverse pregnancy and neonatal outcomes among women in Oman.

Drug utilisation in neonatal units in England and Wales: a national cohort study (2022)
Journal Article
Al-Turkait, A., Szatkowski, L., Choonara, I., & Ojha, S. (2022). Drug utilisation in neonatal units in England and Wales: a national cohort study. European Journal of Clinical Pharmacology, 78(4), 669-677. https://doi.org/10.1007/s00228-021-03267-x

Purpose: To describe drug utilisation patterns in neonatal units. Methods: Retrospective observational cohort study using data held in the National Neonatal Research Database (NNRD) for neonatal units in England and Wales including infants born at 23... Read More about Drug utilisation in neonatal units in England and Wales: a national cohort study.

Anti-reflux medication use in preterm infants (2021)
Journal Article
Binti Abdul Hamid, H., Szatkowski, L., Budge, H., & Ojha, S. (2022). Anti-reflux medication use in preterm infants. Pediatric Research, 92, 520-525. https://doi.org/10.1038/s41390-021-01821-y

Background: Current recommendations do not support the use of anti-reflux medications to treat gastro-oesophageal reflux disease (GORD) among preterm infants. Objective: To describe the prevalence of GORD and the use of anti-reflux medications amongs... Read More about Anti-reflux medication use in preterm infants.

Observational cohort study of changing trends in non-invasive ventilation in very preterm infants and associations with clinical outcomes (2021)
Journal Article
Sand, L., Szatkowski, L., Kwok, T. C., Sharkey, D., Todd, D. A., Budge, H., & Ojha, S. (2022). Observational cohort study of changing trends in non-invasive ventilation in very preterm infants and associations with clinical outcomes. Archives of Disease in Childhood. Fetal and Neonatal Edition, 107(2), 150-155. https://doi.org/10.1136/archdischild-2021-322390

Objective: To determine the change in non-invasive ventilation (NIV) use over time in infants born at <32 weeks’ gestation and the associated clinical outcomes.

Study design: Retrospective cohort study using routinely recorded data from the Nation...

Surgical management of patent ductus arteriosus in pre-term infants - a British paediatric surveillance study (2021)
Journal Article
Warnock, A., Szatkowski, L., Lakshmanan, A., Lee, L., & Kelsall, W. (2021). Surgical management of patent ductus arteriosus in pre-term infants - a British paediatric surveillance study. BMC Pediatrics, 21, Article 270. https://doi.org/10.1186/s12887-021-02734-9

Background: This study aimed to provide UK data describing the incidence of patent ductus arteriosus (PDA) surgery in the neonatal population, including: pre-ligation management, and outcomes until discharge. We used British Paediatric Surveillance U... Read More about Surgical management of patent ductus arteriosus in pre-term infants - a British paediatric surveillance study.

Trends in prescribing of nicotine replacement therapy to pregnant women in primary care in England (2021)
Journal Article
Szatkowski, L., Reeves Vaz, L., Fiaschi, L., Tata, L., & Coleman, T. (2021). Trends in prescribing of nicotine replacement therapy to pregnant women in primary care in England. Nicotine and Tobacco Research, 23(9), 1607-1610. https://doi.org/10.1093/ntr/ntab037

Introduction: Smoking during pregnancy remains common and the English National Health Service (NHS) has recently been directed to prioritise providing cessation support for pregnant women. We investigated the impact on prescribing of stop smoking tre... Read More about Trends in prescribing of nicotine replacement therapy to pregnant women in primary care in England.

Early childhood respiratory morbidity and antibiotic use in ex-preterm infants: A primary care population-based cohort study (2020)
Journal Article
Tan, S., Szatkowski, L., Moreton, W., Fiaschi, L., McKeever, T., Gibson, J., & Sharkey, D. (2020). Early childhood respiratory morbidity and antibiotic use in ex-preterm infants: A primary care population-based cohort study. European Respiratory Journal, 56(1), Article 2000202. https://doi.org/10.1183/13993003.00202-2020

Background Globally, bronchopulmonary dysplasia (BPD) continues to increase in preterm infants. Recent studies exploring subsequent early childhood respiratory morbidity have been small or focused on hospital admissions.

Primary aim Examine early... Read More about Early childhood respiratory morbidity and antibiotic use in ex-preterm infants: A primary care population-based cohort study.