All Outputs (25)

Investigation of Localized Delivery of Diclofenac Sodium from Poly(D,L-Lactic Acid-co-Glycolic Acid)/Poly(Ethylene Glycol) Scaffolds Using an In Vitro Osteoblast Inflammation Model (2014)
Journal Article
Sidney, L. E., Heathman, T. R., Britchford, E., Abed, A. A., Rahman, C. V., & Buttery, L. D. (2015). Investigation of Localized Delivery of Diclofenac Sodium from Poly(D,L-Lactic Acid-co-Glycolic Acid)/Poly(Ethylene Glycol) Scaffolds Using an In Vitro Osteoblast Inflammation Model. Tissue Engineering Part A, 21(1-2), 362-373. https://doi.org/10.1089/ten.tea.2014.0100

Nonunion fractures and large bone defects are significant targets for osteochondral tissue engineering strategies. A major hurdle in the use of these therapies is the foreign body response of the host. Herein, we report the development of a bone tiss... Read More about Investigation of Localized Delivery of Diclofenac Sodium from Poly(D,L-Lactic Acid-co-Glycolic Acid)/Poly(Ethylene Glycol) Scaffolds Using an In Vitro Osteoblast Inflammation Model.

Concise review: evidence for CD34 as a common marker for diverse progenitors (2014)
Journal Article
Sidney, L. E., Branch, M. J., Dunphy, S. E., Dua, H. S., & Hopkinson, A. (2014). Concise review: evidence for CD34 as a common marker for diverse progenitors. STEM CELLS, 32(6), 1380-1389. https://doi.org/10.1002/stem.1661

CD34 is a transmembrane phosphoglycoprotein, first identified on hematopoietic stem and progenitor cells. Clinically, it is associated with the selection and enrichment of hematopoietic stem cells for bone marrow transplants. Due to these historical... Read More about Concise review: evidence for CD34 as a common marker for diverse progenitors.

Comparison of osteogenic differentiation of embryonic stem cells and primary osteoblasts revealed by responses to IL-1β, TNF-α, and IFN-γ (2013)
Journal Article
Sidney, L. E., Kirkham, G. R., & Buttery, L. D. (2013). Comparison of osteogenic differentiation of embryonic stem cells and primary osteoblasts revealed by responses to IL-1β, TNF-α, and IFN-γ. Stem Cells and Development, 23(6), https://doi.org/10.1089/scd.2013.0336

There are well-established approaches for osteogenic differentiation of embryonic stem cells (ESCs), but few show direct comparison with primary osteoblasts or demonstrate differences in response to external factors. Here, we show comparative analysi... Read More about Comparison of osteogenic differentiation of embryonic stem cells and primary osteoblasts revealed by responses to IL-1β, TNF-α, and IFN-γ.

Keeping an Eye on Decellularized Corneas: A Review of Methods, Characterization and Applications (2013)
Journal Article
Wilson, S., Sidney, L., Dunphy, S., Rose, J., & Hopkinson, A. (2013). Keeping an Eye on Decellularized Corneas: A Review of Methods, Characterization and Applications. Journal of Functional Biomaterials, 4(3), 114-161. https://doi.org/10.3390/jfb4030114

The worldwide limited availability of suitable corneal donor tissue has led to the development of alternatives, including keratoprostheses (Kpros) and tissue engineered (TE) constructs. Despite advances in bioscaffold design, there is yet to be a cor... Read More about Keeping an Eye on Decellularized Corneas: A Review of Methods, Characterization and Applications.

Characterization of corneal stromal stem cells with the potential for epithelial transdifferentiation (2013)
Journal Article
Hashmani, K., Branch, M. J., Sidney, L. E., Dhillon, P. S., Verma, M., McIntosh, O. D., …Dua, H. S. (2013). Characterization of corneal stromal stem cells with the potential for epithelial transdifferentiation. Stem Cell Research and Therapy, 4(3), Article 75. https://doi.org/10.1186/scrt226

Introduction: The corneal stroma is being increasingly recognized as a repository for stem cells. Like the limbal and endothelial niches, stromal stem cells often reside in the peripheral cornea and limbus. These peripheral and limbal corneal stromal... Read More about Characterization of corneal stromal stem cells with the potential for epithelial transdifferentiation.