All Outputs (2)

Interspecific Variation in One-Carbon Metabolism within the Ovarian Follicle, Oocyte, and Preimplantation Embryo: Consequences for Epigenetic Programming of DNA Methylation (2021)
Journal Article
Clare, C. E., Pestinger, V., Kwong, W. Y., Tutt, D. A. R., Xu, J., Byrne, H. M., …Sinclair, K. D. (2021). Interspecific Variation in One-Carbon Metabolism within the Ovarian Follicle, Oocyte, and Preimplantation Embryo: Consequences for Epigenetic Programming of DNA Methylation. International Journal of Molecular Sciences, 22(4), Article 1838. https://doi.org/10.3390/ijms22041838

One-carbon (1C) metabolism provides methyl groups for the synthesis and/or methylation 20 of purines and pyrimidines, biogenic amines, proteins and phospholipids. Our understanding of 21 how 1C pathways operate, however, pertains mostly to the (rat)... Read More about Interspecific Variation in One-Carbon Metabolism within the Ovarian Follicle, Oocyte, and Preimplantation Embryo: Consequences for Epigenetic Programming of DNA Methylation.

When maternal periconceptional diet affects neurological development, it’s time to think (2018)
Journal Article
Sinclair, K. D. (2018). When maternal periconceptional diet affects neurological development, it’s time to think. Proceedings of the National Academy of Sciences, 115(31), 7852-7854. https://doi.org/10.1073/pnas.1809471115

There is increasing awareness that the nutritional status of women at the onset of pregnancy can have a profound effect on the general health and well-being of children. However, recent analyses indicate that the majority of women from different soci... Read More about When maternal periconceptional diet affects neurological development, it’s time to think.