All Outputs (2)

Novel mechanisms of resistance to vemurafenib in melanoma – V600E B-Raf reversion and switching VEGF-A splice isoform expression (2014)
Journal Article
Beazley Long, N., Gaston, K., Harper, S. J., Orlando, A., & Bates, D. O. (2015). Novel mechanisms of resistance to vemurafenib in melanoma – V600E B-Raf reversion and switching VEGF-A splice isoform expression. American Journal of Cancer Research, 5(1), 433--441

Targeting activating mutations in the proto-oncogene B-Raf, in melanoma, has led to increases in progression free survival. Treatment with vemurafenib, which inhibits the most common activating-mutated form of B-Raf (B-RafV600E), eventually results i... Read More about Novel mechanisms of resistance to vemurafenib in melanoma – V600E B-Raf reversion and switching VEGF-A splice isoform expression.

Elevation of PRH and inhibition of CK2 retards smooth muscle cell proliferation (2014)
Presentation / Conference Contribution
Wadey, K., Jayaraman, P.-S., Gaston, K., & George, S. (2014). Elevation of PRH and inhibition of CK2 retards smooth muscle cell proliferation. Atherosclerosis, 232(2), e8. https://doi.org/10.1016/j.atherosclerosis.2013.11.023

[Abstract from BAS Autumn meeting 2013, 5-6 September 2013]