Skip to main content

Research Repository

Advanced Search

All Outputs (63)

The isolation of transcription factors from λgt11 cDNA expression libraries: human steroid 5α-reductase 1 has sequence-specific DNA binding activity (1992)
Journal Article
Gaston, K., & Fried, M. (1992). The isolation of transcription factors from λgt11 cDNA expression libraries: human steroid 5α-reductase 1 has sequence-specific DNA binding activity. Nucleic Acids Research, 20(23), 6297-6301. https://doi.org/10.1093/nar/20.23.6297

The Surf-1/Surf-2 bi-directional promoter contains binding sites for at least three transcription factors (Su1, Su2, and Su3). By screening a λgt11 HeLa cell cDNA expression library with a concatenated Su2 factor binding site, we isolated a cDNA whic... Read More about The isolation of transcription factors from λgt11 cDNA expression libraries: human steroid 5α-reductase 1 has sequence-specific DNA binding activity.

A comparison of the DNA bending properties of the DNA binding proteins CRP and TFIID (1992)
Journal Article
Gaston, K., Bell, A., Busby, S., & Fried, M. (1992). A comparison of the DNA bending properties of the DNA binding proteins CRP and TFIID. Nucleic Acids Research, 20(13), 3391-3396. https://doi.org/10.1093/nar/20.13.3391

Protein-induced DNA bending is of importance in the formation of complex nucleoprotein assemblies such as those involved in the initiation of DNA replication or transcription initiation. We have compared the DNA bending characteristics of the Escheri... Read More about A comparison of the DNA bending properties of the DNA binding proteins CRP and TFIID.

The nirB promoter of Escherichia coli: location of nucleotide sequences essential for regulation by oxygen, the FNR protein and nitrite (1988)
Journal Article
Jayaraman, P., Gaston, K., Cole, J., & Busby, S. (1988). The nirB promoter of Escherichia coli: location of nucleotide sequences essential for regulation by oxygen, the FNR protein and nitrite. Molecular Microbiology, 2(4), 527-530. https://doi.org/10.1111/j.1365-2958.1988.tb00059.x

Using recombinant DNA techniques, nested deletions have been made upstream of the Escherichia coli nirB transcription start site and their effects on the regulation of nirB promoter activity have been measured. Nucleotide sequences downstream of −73... Read More about The nirB promoter of Escherichia coli: location of nucleotide sequences essential for regulation by oxygen, the FNR protein and nitrite.