All Outputs (3)

Early apoptosis of porcine alveolar macrophages limits avian influenza virus replication and proinflammatory dysregulation (2015)
Journal Article
Chang, P., Kuchipudi, S. V., Mellits, K., Sebastian, S., James, J., Liu, J., …Chang, K.-C. (2015). Early apoptosis of porcine alveolar macrophages limits avian influenza virus replication and proinflammatory dysregulation. Scientific Reports, 5(17999), https://doi.org/10.1038/srep17999

Pigs are evidently more resistant to avian than swine influenza A viruses, mediated in part through frontline epithelial cells and alveolar macrophages (AM). Although porcine AM (PAM) are crucial in influenza virus control, their mode of control is u... Read More about Early apoptosis of porcine alveolar macrophages limits avian influenza virus replication and proinflammatory dysregulation.

Efficiency of disinfectants against Rotavirus in the presence and absence of organic matter (2015)
Journal Article
Chandler-Bostock, R., & Mellits, K. (in press). Efficiency of disinfectants against Rotavirus in the presence and absence of organic matter. Letters in Applied Microbiology, 61(6), https://doi.org/10.1111/lam.12502

Rotavirus is an enteric pathogen that causes morbidity and mortality in young mammals, including pigs. Outbreaks of rotavirus on commercial farms have a significant economic impact in terms of losses in production. Effective cleaning and disinfection... Read More about Efficiency of disinfectants against Rotavirus in the presence and absence of organic matter.

Diversity of group A rotavirus on a UK pig farm (2015)
Journal Article
Chandler-Bostock, R., Hancox, L., Payne, H., Iturriza-Gomara, M., Daly, J. M., & Mellits, K. (2015). Diversity of group A rotavirus on a UK pig farm. Veterinary Microbiology, 180(3-4), 205-211. https://doi.org/10.1016/j.vetmic.2015.09.009

Group A rotaviruses (GARV) are a significant cause of enteritis in young pigs. The aim of this study was to extend our understanding of the molecular epidemiology of porcine GARV in the UK by investigating the genetic diversity of GARV on a conventio... Read More about Diversity of group A rotavirus on a UK pig farm.