Anaesthetist-controlled versus patient-maintained effect-site targeted propofol sedation during elective primary lower-limb arthroplasty performed under spinal anaesthesia (ACCEPTS): study protocol for a parallel-group randomised comparison trial

Hewson, David W.; Worcester, Frank; Sprinks, James; Smith, Murray D.; Buchanan, Heather; Breedon, Philip; Hardman, Jonathan G.; Bedforth, Nigel M.

doi:10.1186/s13063-019-3228-4

All Outputs (2)

Mathematical and Computational Modelling in Critical Illness (2019)
Journal Article
Laviola, M., Bates, D. G., & Hardman, J. G. (2019). Mathematical and Computational Modelling in Critical Illness. European Respiratory & Pulmonary Diseases, 5(1),

Mathematical and computational modelling are assuming a prominent role in investigating the complex pathophysiological states and therapeutic strategies in critical illness. This editorial briefly illustrates the models of the respiratory and cardiov... Read More about Mathematical and Computational Modelling in Critical Illness.

Anaesthetist-controlled versus patient-maintained effect-site targeted propofol sedation during elective primary lower-limb arthroplasty performed under spinal anaesthesia (ACCEPTS): study protocol for a parallel-group randomised comparison trial (2019)
Journal Article
Hewson, D. W., Worcester, F., Sprinks, J., Smith, M. D., Buchanan, H., Breedon, P., …Bedforth, N. M. (2019). Anaesthetist-controlled versus patient-maintained effect-site targeted propofol sedation during elective primary lower-limb arthroplasty performed under spinal anaesthesia (ACCEPTS): study protocol for a parallel-group randomised comparison trial. Trials, 20(1), Article 129. https://doi.org/10.1186/s13063-019-3228-4

Background The clinical efficacy of effect-site targeted patient-maintained propofol sedation (PMPS) compared to anaesthetist-controlled propofol sedation (ACPS) for patients undergoing awake joint replacement surgery is currently unknown. There is... Read More about Anaesthetist-controlled versus patient-maintained effect-site targeted propofol sedation during elective primary lower-limb arthroplasty performed under spinal anaesthesia (ACCEPTS): study protocol for a parallel-group randomised comparison trial.