All Outputs (28)

3D printing of five-in-one dose combination polypill with defined immediate and sustained release profiles (2015)
Journal Article

We have used three dimensional (3D) extrusion printing to manufacture a multi-active solid dosage form or so called polypill. This contains five compartmentalised drugs with two independently controlled and well-defined release profiles. This polypil... Read More about 3D printing of five-in-one dose combination polypill with defined immediate and sustained release profiles.

Biomimetic Three-Dimensional Gradient of GAG-Binding Enhanced Transduction Proteins for Stem Cell Differentiation (2015)
Journal Article

Cell and protein compatible 3D bioprinting of mechanically strong constructs for bone repair (2015)
Journal Article

© 2015 IOP Publishing Ltd. Rapid prototyping of bone tissue engineering constructs often utilizes elevated temperatures, organic solvents and/or UV light for materials processing. These harsh conditions may prevent the incorporation of cells and ther... Read More about Cell and protein compatible 3D bioprinting of mechanically strong constructs for bone repair.

Modelling and Prediction of Bacterial Attachment to Polymers (2013)
Journal Article

Infection by pathogenic bacteria on implanted and indwelling medical devices during surgery causes large morbidity and mortality worldwide. Attempts to ameliorate this important medical issue have included development of antimicrobial surfaces on mat... Read More about Modelling and Prediction of Bacterial Attachment to Polymers.

Discovery of novel materials with broad resistance to bacterial attachment using combinatorial polymer microarrays (2013)
Journal Article

A new class of bacteria-attachment-resistant materials is discovered using a multi-generation polymer microarray methodology that reduces bacterial attachment by up to 99.3% compared with a leading commercially available silver hydrogel anti-bacteria... Read More about Discovery of novel materials with broad resistance to bacterial attachment using combinatorial polymer microarrays.

Modelling human embryoid body cell adhesion to a combinatorial library of polymer surfaces (2012)
Journal Article

Designing materials to control biology is an intense focus of biomaterials and regenerative medicine research. Discovering and designing materials with appropriate biological compatibility or active control of cells and tissues is being increasingly... Read More about Modelling human embryoid body cell adhesion to a combinatorial library of polymer surfaces.

Combinatorial discovery of polymers resistant to bacterial attachment (2012)
Journal Article

Bacterial attachment and subsequent biofilm formation pose key challenges to the optimal performance of medical devices. In this study, we determined the attachment of selected bacterial species to hundreds of polymeric materials in a high-throughput... Read More about Combinatorial discovery of polymers resistant to bacterial attachment.

Polymers with hydro-responsive topography identi?ed using high throughput AFM of an acrylate microarray (2011)
Journal Article

Atomic force microscopy has been applied to an acrylate polymer microarray to achieve a full topographic characterisation. This process discovered a small number of hydro-responsive materials created from monomers with disparate hydrophilicities that... Read More about Polymers with hydro-responsive topography identi?ed using high throughput AFM of an acrylate microarray.