Orally-delivered insulin-peptide nanocomplexes enhance transcytosis from cellular depots and improve diabetic blood glucose control
(2023)
Journal Article
Rehmani, S., McLaughlin, C. M., Eltaher, H. M., Moffett, R. C., Flatt, P. R., & Dixon, J. E. (2023). Orally-delivered insulin-peptide nanocomplexes enhance transcytosis from cellular depots and improve diabetic blood glucose control. Journal of Controlled Release, 360, 93-109. https://doi.org/10.1016/j.jconrel.2023.06.006
Insulin regulates blood glucose levels, and is the mainstay for the treatment of type-1 diabetes and type-2 when other drugs provide inadequate control. Therefore, effective oral Insulin delivery would be a significant advance in drug delivery. Herei... Read More about Orally-delivered insulin-peptide nanocomplexes enhance transcytosis from cellular depots and improve diabetic blood glucose control.