Residues contributing to drug transport by ABCG2 are localised to multiple drug-binding pockets

Cox, Megan H.; Kapoor, Parth; Briggs, Deborah A.; Kerr, Ian D.

doi:10.1042/BCJ20170923

All Outputs (2)

MBRS-21. EXTRACELLULAR VESICLES FROM METASTATIC MEDULLOBLASTOMA CELL LINES CARRY mRNAs KNOWN TO CORRELATE WITH METASTATIC DISEASE (2018)
Presentation / Conference Contribution
Jackson, H. K., Linke, F., Kerr, I. D., & Coyle, B. MBRS-21. EXTRACELLULAR VESICLES FROM METASTATIC MEDULLOBLASTOMA CELL LINES CARRY mRNAs KNOWN TO CORRELATE WITH METASTATIC DISEASE

Residues contributing to drug transport by ABCG2 are localised to multiple drug-binding pockets (2018)
Journal Article
Cox, M. H., Kapoor, P., Briggs, D. A., & Kerr, I. D. (2018). Residues contributing to drug transport by ABCG2 are localised to multiple drug-binding pockets. Biochemical Journal, 475(9), https://doi.org/10.1042/BCJ20170923

Multidrug binding and transport by the ATP binding cassette transporter ABCG2 is a factor in the clinical resistance to chemotherapy in leukaemia, and a contributory factor to the pharmacokinetic profiles of many other prescribed drugs. Despite its i... Read More about Residues contributing to drug transport by ABCG2 are localised to multiple drug-binding pockets.