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Housing temperature modulates the impact of diet-induced rise in fat mass on adipose tissue before and during pregnancy in rats (2019)
Journal Article
Albustanji, L., Perez, G. S., Alharethi, E., Aldiss, P., Bloor, I., Barreto-Medeiros, J. M., …Dellschaft, N. (2019). Housing temperature modulates the impact of diet-induced rise in fat mass on adipose tissue before and during pregnancy in rats. Frontiers in Physiology, 10, https://doi.org/10.3389/fphys.2019.00209

Aim: To investigate whether housing temperature influences rat adiposity, and the extent it is modified by diet and/or pregnancy. Housing temperature impacts on brown adipose tissue, that possess a unique uncoupling protein (UCP) 1, which, when activ... Read More about Housing temperature modulates the impact of diet-induced rise in fat mass on adipose tissue before and during pregnancy in rats.

Low temperature exposure induces browning of bone marrow stem cell derived adipocytes in vitro (2018)
Journal Article
Velickovic, K., Lugo-Leija, H. A., Bloor, I., Law, J., Sacks, H., Symonds, M. E., & Sottile, V. (2018). Low temperature exposure induces browning of bone marrow stem cell derived adipocytes in vitro. Scientific Reports, 8, Article 4974. https://doi.org/10.1038/s41598-018-23267-9

Brown and beige adipocytes are characterised as expressing the unique mitochondrial uncoupling protein (UCP)1 for which the primary stimulus in vivo is cold exposure. The extent to which cold-induced UCP1 activation can also be achieved in vitro, and... Read More about Low temperature exposure induces browning of bone marrow stem cell derived adipocytes in vitro.

Sex differences in metabolic and adipose tissue responses to juvenile-onset obesity in sheep (2013)
Journal Article
Bloor, I. D., Sébert, S. P., Saroha, V., Gardner, D. S., Keisler, D. H., Budge, H., …Mahajan, R. P. (2013). Sex differences in metabolic and adipose tissue responses to juvenile-onset obesity in sheep. Endocrinology, 154(10), https://doi.org/10.1210/en.2013-1207

Sex is a major factor determining adipose tissue distribution and the subsequent adverse effects of obesity-related disease including type 2 diabetes. The role of gender on juvenile obesity and the accompanying metabolic and inflammatory responses is... Read More about Sex differences in metabolic and adipose tissue responses to juvenile-onset obesity in sheep.