All Outputs (4)

Direct contact-mediated non-viral gene therapy using thermo-sensitive hydrogel-coated dressings (2022)
Journal Article
Eltaher, H. M., Blokpoel Ferreras, L. A., Jalal, A. R., & Dixon, J. (2022). Direct contact-mediated non-viral gene therapy using thermo-sensitive hydrogel-coated dressings. Biomaterials Advances, 143, Article 213177. https://doi.org/10.1016/j.bioadv.2022.213177

Nanotechnologies are being increasingly applied as systems for peptide and nucleic acid macromolecule drug delivery. However systemic targeting of these, or efficient topical and localized delivery remains an issue. A controlled release system that c... Read More about Direct contact-mediated non-viral gene therapy using thermo-sensitive hydrogel-coated dressings.

Prodigiosin-Functionalized Probiotic Ghosts as a Bioinspired Combination Against Colorectal Cancer Cells (2022)
Journal Article
Saleh, N., Mahmoud, H. E., Eltaher, H., Helmy, M., El-Khordagui, L., & Hussein, A. A. (2023). Prodigiosin-Functionalized Probiotic Ghosts as a Bioinspired Combination Against Colorectal Cancer Cells. Probiotics and Antimicrobial Proteins, 15(5), 1271-1286. https://doi.org/10.1007/s12602-022-09980-y

Lactobacillus acidophilus ghosts (LAGs) with the unique safety of a probiotic, inherent tropism for colon cells, and multiple bioactivities offer promise as drug carriers for colon targeting. Our objective was to evaluate LAGs functionalized with pro... Read More about Prodigiosin-Functionalized Probiotic Ghosts as a Bioinspired Combination Against Colorectal Cancer Cells.

Abstract 1917 NON‐VIRAL GENE EDITING APPROACHES TO GENETICALLY AUGMENT AND CORRECT CYSTIC FIBROSIS USING MUCUS PENETRATING PEPTIDE NANOPARTICLES (2022)
Presentation / Conference Contribution
Savage, A. M., Eltaher, H., Soo Suk, J., & Dixon, J. E. (2022). Abstract 1917 NON‐VIRAL GENE EDITING APPROACHES TO GENETICALLY AUGMENT AND CORRECT CYSTIC FIBROSIS USING MUCUS PENETRATING PEPTIDE NANOPARTICLES. Tissue Engineering Part A, 28(S1),

RAPID INTRAOPERATIVE GENETIC AUGMENTATION OF AUTOGRAFTS FOR RECONSTRUCTIVE SURGERY OF SEVERE TRAUMA (2022)
Presentation / Conference Contribution
Dixon, J., Thi Mai, T., McLaren, J., Ollivere, B., Scammell, B., & Eltaher, H. (2022). RAPID INTRAOPERATIVE GENETIC AUGMENTATION OF AUTOGRAFTS FOR RECONSTRUCTIVE SURGERY OF SEVERE TRAUMA. Tissue Engineering: Parts A, B, and C, 28(S1),

Survivors with severe tissue injury have unmet clinical needs for better bone and soft tissue regeneration. Specifically they have progressive tissue loss due to inflammation, necrosis, infection and the development of critical size bone defects is a... Read More about RAPID INTRAOPERATIVE GENETIC AUGMENTATION OF AUTOGRAFTS FOR RECONSTRUCTIVE SURGERY OF SEVERE TRAUMA.