All Outputs (2)

Association between serum urate and flares in people with gout and evidence for surrogate status: a secondary analysis of two randomised controlled trials (2021)
Journal Article
Stamp, L. K., Frampton, C., Morillon, M. B., Taylor, W. J., Dalbeth, N., Singh, J. A., …Christensen, R. (2022). Association between serum urate and flares in people with gout and evidence for surrogate status: a secondary analysis of two randomised controlled trials. The Lancet Rheumatology, 4(1), e53-e60. https://doi.org/10.1016/s2665-9913%2821%2900319-2

Background
Use of serum urate as a treatment target and outcome measure has become controversial in view of the 2017 American College of Physicians guidelines, which advocated a treat-to-symptom rather than a treat-to-target serum urate approach to... Read More about Association between serum urate and flares in people with gout and evidence for surrogate status: a secondary analysis of two randomised controlled trials.

Genome-wide association scan of neuropathic pain symptoms post total joint replacement highlights a variant in the protein-kinase C gene (2017)
Journal Article
Warner, S. C., van Meurs, J. B., Schiphof, D., Bierma-Zeinstra, S. M., Hofman, A., Uitterlinden, A. G., …Valdes, A. M. (in press). Genome-wide association scan of neuropathic pain symptoms post total joint replacement highlights a variant in the protein-kinase C gene. European Journal of Human Genetics, https://doi.org/10.1038/ejhg.2016.196

Neuropathic pain-like joint symptoms (NP) are seen in a proportion of individuals diagnosed with osteoarthritis (OA) and post total joint replacement (TJR). In this study, we performed a genome-wide association study (GWAS) using NP as defined by the... Read More about Genome-wide association scan of neuropathic pain symptoms post total joint replacement highlights a variant in the protein-kinase C gene.