All Outputs (50)

The normal inhibition of associations is impaired by clonidine in Tourette syndrome (2011)
Journal Article
Kantini, E., Cassaday, H. J., Hollis, C., & Jackson, G. M. (2011). The normal inhibition of associations is impaired by clonidine in Tourette syndrome. Journal of the Canadian Academy of Child and Adolescent Psychiatry = Journal de l'Academie canadienne de psychiatrie de l'enfant et de l'adolescent, 20(2),

Objective: We examined the inhibition of stimulus-stimulus associations (formally ‘conditioned inhibition’) in Tourette syndrome (TS). Method: The present study used video game style conditioned inhibition procedures suitable for children and adolesc... Read More about The normal inhibition of associations is impaired by clonidine in Tourette syndrome.

Associative learning in ADHD: improved expression under methylphenidate (2011)
Journal Article
Kantini, E., Cassaday, H. J., Batty, M. J., Hollis, C., & Jackson, G. M. (2011). Associative learning in ADHD: improved expression under methylphenidate. Open Journal of Psychiatry, 1(2), https://doi.org/10.4236/ojpsych.2011.12004

Attention Deficit/Hyperactivity Disorder (ADHD) is characterised by developmentally inappropriate levels of inattention, impulsivity and hyperactivity. As might be expected of a disorder in which inhibitory deficits form part of the diagnostic criter... Read More about Associative learning in ADHD: improved expression under methylphenidate.

Impaired Pavlovian conditioned inhibition in offenders with personality disorders (2011)
Journal Article
He, Z., Cassaday, H. J., Howard, R. C., Khalifa, N., & Bonardi, C. (2011). Impaired Pavlovian conditioned inhibition in offenders with personality disorders. Quarterly Journal of Experimental Psychology, 64(12), https://doi.org/10.1080/17470218.2011.616933

Certain types of violent offending are often accompanied by evidence of personality disorders (PDs), a range of heterogeneous conditions characterised by disinhibited behaviours that are generally described as impulsive. The tasks previously used to... Read More about Impaired Pavlovian conditioned inhibition in offenders with personality disorders.

Dissociable roles of dopamine within the core and medial shell of the nucleus accumbens in memory for objects and place (2010)
Journal Article
Nelson, A. J., Thur, K. E., Marsden, C. A., & Cassaday, H. J. (2010). Dissociable roles of dopamine within the core and medial shell of the nucleus accumbens in memory for objects and place. Behavioral Neuroscience, 124(6), https://doi.org/10.1037/a0021114

There is increasing focus on the role of the nucleus accumbens (NAc) in learning and memory, but there is little consensus as to how the core and medial shell subregions of the NAc contribute to these processes. In the current experiments, we used sp... Read More about Dissociable roles of dopamine within the core and medial shell of the nucleus accumbens in memory for objects and place.

Catecholaminergic depletion within the prelimbic medial prefrontal cortex enhances latent inhibition (2010)
Journal Article
Nelson, A. J., Thur, K. E., Marsden, C., & Cassaday, H. J. (2010). Catecholaminergic depletion within the prelimbic medial prefrontal cortex enhances latent inhibition. Neuroscience, 170(1), https://doi.org/10.1016/j.neuroscience.2010.06.066

Latent inhibition (LI) refers to the reduction in conditioning to a stimulus that has received repeated non-reinforced pre-exposure. Investigations into the neural substrates of LI have focused on the nucleus accumbens (NAc) and its inputs from the h... Read More about Catecholaminergic depletion within the prelimbic medial prefrontal cortex enhances latent inhibition.

Corticosterone differences rather than social housing predict performance of T-maze alternation in male CD-1 mice (2009)
Journal Article
Fitchett, A. E., Barnard, C. J., & Cassaday, H. J. (2009). Corticosterone differences rather than social housing predict performance of T-maze alternation in male CD-1 mice. Animal Welfare Journal, 18(1),

This study examined the effects of social housing manipulations on body weight, corticosterone levels, and performance of T-maze alternation in male CD-1 mice. Males that adopted a dominant social rank were heavier than those that adopted a subordina... Read More about Corticosterone differences rather than social housing predict performance of T-maze alternation in male CD-1 mice.

There’s no place like home: cage odours and place preference in subordinate CD-1 male mice (2006)
Journal Article
Fitchett, A. E., Barnard, C. J., & Cassaday, H. J. (2006). There’s no place like home: cage odours and place preference in subordinate CD-1 male mice. Physiology and Behavior, 87(5), https://doi.org/10.1016/j.physbeh.2006.02.010

Prior studies using mice have shown that scent marks are an important source of information and can cause behavioural changes in other individuals. Studies have also shown that scent marks in the environment can affect the outcome of social interacti... Read More about There’s no place like home: cage odours and place preference in subordinate CD-1 male mice.

Effect of orexin-B-saporin-induced lesions of the lateral hypothalamus on performance on a progressive ratio schedule
Journal Article
Olarte-Sánchez, C., Valencia Torres, L., Body, S., Cassaday, H. J., Bradshaw, C., & Szabadi, E. Effect of orexin-B-saporin-induced lesions of the lateral hypothalamus on performance on a progressive ratio schedule. Journal of Psychopharmacology, 26(6), https://doi.org/10.1177/0269881111409607

It has been suggested that a sub-population of orexinergic neurones whose somata lie in the lateral hypothalamic area (LHA) play an important role in regulating the reinforcing value of both food and drugs. This experiment examined the effect of disr... Read More about Effect of orexin-B-saporin-induced lesions of the lateral hypothalamus on performance on a progressive ratio schedule.

Effects of SKF-83566 and haloperidol on performance on progressive ratio schedules maintained by sucrose and corn oil reinforcement: quantitative analysis using a new model derived from the Mathematical Principles of Reinforcement (MPR)
Journal Article
Olarte-Sánchez, C., Valencia-Torres, L., Cassaday, H. J., Bradshaw, C., & Szabadi, E. Effects of SKF-83566 and haloperidol on performance on progressive ratio schedules maintained by sucrose and corn oil reinforcement: quantitative analysis using a new model derived from the Mathematical Principles of Reinforcement (MPR). Psychopharmacology, 230(4), https://doi.org/10.1007/s00213-013-3189-3

Rationale Mathematical models can assist the interpretation of the effects of interventions on schedule-controlled behaviour and help to differentiate between processes that may be confounded in traditional performance measures such as response rate... Read More about Effects of SKF-83566 and haloperidol on performance on progressive ratio schedules maintained by sucrose and corn oil reinforcement: quantitative analysis using a new model derived from the Mathematical Principles of Reinforcement (MPR).

What’s special about the ethical challenges of studying disorders with altered brain activity?
Book Chapter
Cassaday, H. J. What’s special about the ethical challenges of studying disorders with altered brain activity?. In G. Lee, J. Illes, & F. Ohl (Eds.), Ethical issues in behavioral neuroscience. Springer-Verlag. https://doi.org/10.1007/7854_2014_333

Where there is no viable alternative, studies of neuronal activity are conducted on animals. The use of animals, particularly for invasive studies of the brain, raises a number of ethical issues. Practical or normative ethics are enforced by legislat... Read More about What’s special about the ethical challenges of studying disorders with altered brain activity?.