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All Outputs (32)

UK horse owners and veterinary practitioners' experiences of decision‐making for critical cases of colic (2024)
Journal Article
Burrell, K. L., Burford, J. H., England, G. C., & Freeman, S. L. (2024). UK horse owners and veterinary practitioners' experiences of decision‐making for critical cases of colic. Equine Veterinary Journal, https://doi.org/10.1111/evj.14124

Background: The survival of horses diagnosed with critical colic (requiring referral or euthanasia) relies on rapid and effective decision-making by the owner and veterinary practitioner. Objectives: To explore UK horse owners' and veterinary practit... Read More about UK horse owners and veterinary practitioners' experiences of decision‐making for critical cases of colic.

Horse owners' and veterinary practitioners' experiences of decision-making for critical cases of colic (2024)
Preprint / Working Paper
Freeman, S., Burrell, K., Burford, J., & England, G. Horse owners' and veterinary practitioners' experiences of decision-making for critical cases of colic

Background: The survival of horses diagnosed with critical colic relies on rapid and effective decision-making by owner and veterinary practitioner. Objectives: To explore horse owners’ and veterinary practitioners’ experiences of decision-making for... Read More about Horse owners' and veterinary practitioners' experiences of decision-making for critical cases of colic.

INSL3 Variation in Dogs Following Suppression and Recovery of the HPG Axis (2024)
Journal Article
Anand-Ivell, R., Coutinho, A. R., Dai, Y., England, G., Goericke-Pesch, S., & Ivell, R. (2024). INSL3 Variation in Dogs Following Suppression and Recovery of the HPG Axis. Animals, 14(5), Article 675. https://doi.org/10.3390/ani14050675

Insulin-like peptide 3 (INSL3) is a constitutive product of mature, adult-type Leydig cells of the testes and consequently in most mammals is an ideal biomarker with which to monitor pubertal development. A new heterologous time-resolved fluorescence... Read More about INSL3 Variation in Dogs Following Suppression and Recovery of the HPG Axis.

Luteal phase decrease in packed cell volume in healthy non‐pregnant and pregnant bitches (2023)
Journal Article
Moxon, R., Dutton Worsfold, R., Davis, J., Adams, W., & England, G. C. W. (2023). Luteal phase decrease in packed cell volume in healthy non‐pregnant and pregnant bitches. Veterinary Medicine and Science, https://doi.org/10.1002/vms3.1195

Objectives: To establish packed cell volume (PCV) ranges for non‐pregnant, pregnant and post‐partum bitches from day 10 of proestrus, investigating any relationship with parity and litter size. Methods: This prospective cohort study used 37 healthy b... Read More about Luteal phase decrease in packed cell volume in healthy non‐pregnant and pregnant bitches.

A Prospective Cohort Study Investigating the Impact of Neutering Bitches Prepubertally or Post-Pubertally on Physical Development (2023)
Journal Article
Moxon, R., Freeman, S. L., Payne, R., Godfrey-Hunt, J., Corr, S., & England, G. C. W. (2023). A Prospective Cohort Study Investigating the Impact of Neutering Bitches Prepubertally or Post-Pubertally on Physical Development. Animals, 13(9), Article 1431. https://doi.org/10.3390/ani13091431

No previous large prospective cohort studies have been identified that have investigated the impact of the surgical neutering of bitches before or after known puberty on their growth and physical development. This study was designed to examine the da... Read More about A Prospective Cohort Study Investigating the Impact of Neutering Bitches Prepubertally or Post-Pubertally on Physical Development.

A Prospective Cohort Study Investigating the Behavioural Development of Bitches in a Guide Dog Training Programme Neutered Prepubertally or Post-Pubertally (2022)
Journal Article
Moxon, R., Freeman, S., Payne, R., Corr, S., & England, G. C. W. (2022). A Prospective Cohort Study Investigating the Behavioural Development of Bitches in a Guide Dog Training Programme Neutered Prepubertally or Post-Pubertally. Frontiers in Veterinary Science, 9, Article 902775. https://doi.org/10.3389/fvets.2022.902775

There are few studies that investigate the effect of neutering bitches before or after puberty. The majority of current literature examining the impact of the timing of neutering on health and behaviour has used age rather than the onset of puberty a... Read More about A Prospective Cohort Study Investigating the Behavioural Development of Bitches in a Guide Dog Training Programme Neutered Prepubertally or Post-Pubertally.

Comparative pathology of dog and human prostate cancer (2021)
Journal Article
Ryman-Tubb, T., Lothion-Roy, J. H., Metzler, V. M., Harris, A. E., Robinson, B. D., Rizvanov, A. A., …de Brot, S. (2022). Comparative pathology of dog and human prostate cancer. Veterinary Medicine and Science, 8(1), 110-120. https://doi.org/10.1002/vms3.642

Though relatively rare in dogs, prostate cancer (PCa) is the most common non-cutaneous cancer in men. Human and canine prostate glands share many functional, anatomical and physiological features. Due to these similarities, canine PCa has been propos... Read More about Comparative pathology of dog and human prostate cancer.

Environmental chemicals in dog testes reflect their geographical source and may be associated with altered pathology (2021)
Journal Article
Sumner, R. N., Byers, A., Zhang, Z., Agerholm, J. S., Lindh, L., England, G. C. W., & Lea, R. G. (2021). Environmental chemicals in dog testes reflect their geographical source and may be associated with altered pathology. Scientific Reports, 11, Article 7361. https://doi.org/10.1038/s41598-021-86805-y

In humans and dogs, a temporal decline in semen quality and increased incidence of testicular cancer is hypothesised to be associated with exposure to anthropogenic chemicals, particularly during fetal development. Human studies suggest that differen... Read More about Environmental chemicals in dog testes reflect their geographical source and may be associated with altered pathology.

Contrast-Enhanced Ultrasound Imaging of Prostate Gland in Neutered Dogs (2021)
Journal Article
Spada, S., England, G. C. W., Vignoli, M., Carluccio, A., & Russo, M. (2021). Contrast-Enhanced Ultrasound Imaging of Prostate Gland in Neutered Dogs. Animals, 11(2), Article 559. https://doi.org/10.3390/ani11020559

Prostatic neoplasia (PN) occurs in 5–7% of dogs with prostatic disease, with castrated dogs having the same or higher prevalence when compared to intact dogs. Considering the promising results achieved by performing contrast-enhanced ultrasound (CEUS... Read More about Contrast-Enhanced Ultrasound Imaging of Prostate Gland in Neutered Dogs.

Cross‐sectional study of UK horse owner's purchase and euthanasia decision‐making for their horse (2021)
Journal Article
Clough, H., Roshier, M., England, G., Burford, J., & Freeman, S. (2021). Cross‐sectional study of UK horse owner's purchase and euthanasia decision‐making for their horse. Veterinary Record, 188(6), Article e56. https://doi.org/10.1002/vetr.56

Background: This cross-sectional study aimed to investigate factors affecting horse owners’ purchase and euthanasia decisions that had been identified in a qualitative study.
Methods: An online survey on horse owners’ purchase and euthanasia decisi... Read More about Cross‐sectional study of UK horse owner's purchase and euthanasia decision‐making for their horse.

Normal and abnormal response to sperm deposition in female dogs: A review and new hypotheses for endometritis (2020)
Journal Article
England, G., Rijsselaere, T., Campbell, A., Moxon, R., & Freeman, S. (2021). Normal and abnormal response to sperm deposition in female dogs: A review and new hypotheses for endometritis. Theriogenology, 159, 176-183. https://doi.org/10.1016/j.theriogenology.2020.10.013

In mammalian species there are significant physiological responses of the female reproductive tract to the deposition of sperm. These are particularly notable in species where sperm are deposited directly into the uterus, and function both to facilit... Read More about Normal and abnormal response to sperm deposition in female dogs: A review and new hypotheses for endometritis.

Indicators of ‘critical’ outcomes in 941 horses seen ‘out-of-hours’ for colic (2020)
Journal Article
Bowden, A., England, G. C. W., Brennan, M. L., Mair, T. S., Furness, W. A., Freeman, S. L., & Burford, J. H. (2020). Indicators of ‘critical’ outcomes in 941 horses seen ‘out-of-hours’ for colic. Veterinary Record, 187(12), 492-492. https://doi.org/10.1136/vr.105881

Background: This study aimed to describe the presentation and outcomes of horses with signs of colic (abdominal pain) seen 'out-of-hours' in equine practice. Methods: This was a retrospective study of horses seen 'out-of-hours' with colic by two equi... Read More about Indicators of ‘critical’ outcomes in 941 horses seen ‘out-of-hours’ for colic.

Retrospective case series to identify the most common conditions seen ‘out-of-hours’ by first-opinion equine veterinary practitioners (2020)
Journal Article
Boynova, P., Bowden, A., Boynova, P., England, G. C. W., Brennan, M. L., Mair, T. S., …Burford, J. H. (2020). Retrospective case series to identify the most common conditions seen ‘out-of-hours’ by first-opinion equine veterinary practitioners. Veterinary Record, 187(10), 404-404. https://doi.org/10.1136/vr.105880

Background: The study aim was to describe conditions seen 'out-of-hours' in equine practice. Methods: This was a retrospective case series of first opinion 'out-of-hours' cases seen at two equine practices between 2011 and 2013. Data were retrieved o... Read More about Retrospective case series to identify the most common conditions seen ‘out-of-hours’ by first-opinion equine veterinary practitioners.

Teenage dogs? Evidence for adolescent-phase conflict behaviour and an association between attachment to humans and pubertal timing in the domestic dog (2020)
Journal Article
Asher, L., England, G. C. W., Sommerville, R., & Harvey, N. D. (2020). Teenage dogs? Evidence for adolescent-phase conflict behaviour and an association between attachment to humans and pubertal timing in the domestic dog. Biology Letters, 16(5), Article 20200097. https://doi.org/10.1098/rsbl.2020.0097

The relationship between parent and child changes around adolescence, with children believed to have: (i) an earlier puberty if they have less secure attachments to their carer; (ii) a phase of increased conflict behaviour toward their carer; and (ii... Read More about Teenage dogs? Evidence for adolescent-phase conflict behaviour and an association between attachment to humans and pubertal timing in the domestic dog.

A scoping review of the current literature exploring the nature of the horse-human relationship (2019)
Journal Article
Clough, H. .., Burford, J., England, G., & Freeman, S. L. (2019). A scoping review of the current literature exploring the nature of the horse-human relationship. Veterinary Evidence, 4(4), https://doi.org/10.18849/ve.v4i4.240

Objective: To perform a scoping review of the current evidence on the horse-human relationship.

Background: The horse-human relationship has a significant impact on how horse owners care for and make decisions for their horse.

Evidentiary value... Read More about A scoping review of the current literature exploring the nature of the horse-human relationship.

Cross-sectional study of horse owners’ knowledge, and opinions on recognising colic in the horse (2019)
Journal Article
Bowden, A., Burford, J., Brennan, M., England, G., & Freeman, S. (2019). Cross-sectional study of horse owners’ knowledge, and opinions on recognising colic in the horse. Equine Veterinary Journal, https://doi.org/10.1111/evj.13173

Background
Colic is the most common emergency problem in the horse. An owner’s ability to recognise colic and seek assistance is a critical first step in determining case outcome.

Objectives
The aim of this study was to assess horse owners’ know... Read More about Cross-sectional study of horse owners’ knowledge, and opinions on recognising colic in the horse.

Risk factors for acute abdominal pain (colic) in the adult horse: A scoping review of risk factors, and a systematic review of the effect of management-related changes (2019)
Journal Article
Curtis, L., Burford, J. H., England, G. C. W., & Freeman, S. L. (2019). Risk factors for acute abdominal pain (colic) in the adult horse: A scoping review of risk factors, and a systematic review of the effect of management-related changes. PLoS ONE, 14(7), 1-32. https://doi.org/10.1371/journal.pone.0219307

Acute abdominal pain (colic) is the most common reason for emergency veterinary treatment in the horse. Consolidation of data through a systematic review is important to inform evidence-based medicine and clinical guidelines, but there are currently... Read More about Risk factors for acute abdominal pain (colic) in the adult horse: A scoping review of risk factors, and a systematic review of the effect of management-related changes.

Emergency Conditions in Horses: Opinions and Decision Making of Livery Yard Owners (2019)
Journal Article
Bowden, A., Burford, J., Brennan, M., England, G., & Freeman, S. (2019). Emergency Conditions in Horses: Opinions and Decision Making of Livery Yard Owners. Veterinary Evidence, 4(2), https://doi.org/10.18849/ve.v4i2.199

Objective: The aim of this study was to evaluate equine livery yard owners’ opinions of emergency conditions, and to identify factors influencing emergency decision making in the horse.

Background: There is limited data on horse owners’ opinions a... Read More about Emergency Conditions in Horses: Opinions and Decision Making of Livery Yard Owners.

Seasonality in oestrus and litter size in an assistance dog breeding colony in the United Kingdom (2017)
Journal Article
Wigham, E. E., Moxon, R., England, G. C., Wood, J. L., & Morters, M. K. (2017). Seasonality in oestrus and litter size in an assistance dog breeding colony in the United Kingdom. Veterinary Record, 181(14), 371-371. https://doi.org/10.1136/vr.104217

Evidence of seasonality in oestrus in bitches within specialist breeding programmes, such as those for assistance dogs, may support colony management through tailoring the distribution of resources required for breeding throughout the year. However,... Read More about Seasonality in oestrus and litter size in an assistance dog breeding colony in the United Kingdom.