Digital pathology for reporting histopathology samples, including cancer screening samples – definitive evidence from a multisite study

Azam, Ayesha S; Tsang, Yee‐Wah; Thirlwall, Jenny; Kimani, Peter K; Sah, Shatrughan; Gopalakrishnan, Kishore; Boyd, Clinton; Loughrey, Maurice B; Kelly, Paul J; Boyle, David P; Salto‐Tellez, Manuel; Clark, David; Ellis, Ian O; Ilyas, Mohammad; Rakha, Emad; Bickers, Adam; Roberts, Ian S D; Soares, Maria F; Neil, Desley A H; Takyi, Abi; Raveendran, Sinthuri; Hero, Emily; Evans, Harriet; Osman, Rania; Fatima, Khunsha; Hughes, Rhian W; McIntosh, Stuart A; Moran, Gordon W; Ortiz‐Fernandez‐Sordo, Jacobo; Rajpoot, Nasir M; Storey, Ben; Ahmed, Imtiaz; Dunn, Janet A; Hiller, Louise; Snead, David R J

doi:10.1111/his.15129

All Outputs (3)

ATF4 as a Prognostic Marker and Modulator of Glutamine Metabolism in Estrogen Receptor Positive Breast Cancer (2024)
Journal Article
Patel, R., Alfarsi, L. H., El-Ansari, R., Masisi, B. K., Erkan, B., Fakroun, A., …Green, A. R. (in press). ATF4 as a Prognostic Marker and Modulator of Glutamine Metabolism in Estrogen Receptor Positive Breast Cancer. Pathobiology, https://doi.org/10.1159/000539564

Purpose: ATF4, a stress-responsive transcription factor that upregulates adaptive genes, is a potential prognostic marker and modulator of glutamine metabolism in breast cancer. However, its exact role remains to be elucidated. Methods: ATF4 expre... Read More about ATF4 as a Prognostic Marker and Modulator of Glutamine Metabolism in Estrogen Receptor Positive Breast Cancer.

Deciphering the Clinical Behaviour of Invasive Lobular Carcinoma of the Breast Defines an Aggressive Subtype (2024)
Journal Article
Makhlouf, S., Atallah, N. M., Polotto, S., Lee, A. H., Green, A. R., & Rakha, E. A. (2024). Deciphering the Clinical Behaviour of Invasive Lobular Carcinoma of the Breast Defines an Aggressive Subtype. Cancers, 16(10), Article 1893. https://doi.org/10.3390/cancers16101893

Background: Invasive lobular carcinoma (ILC), the most common special type of breast cancer (BC), has unique clinical behaviour and is different from invasive ductal carcinoma of no special type (IDC-NST). However, ILC further comprises a diverse gro... Read More about Deciphering the Clinical Behaviour of Invasive Lobular Carcinoma of the Breast Defines an Aggressive Subtype.

Digital pathology for reporting histopathology samples, including cancer screening samples – definitive evidence from a multisite study (2024)
Journal Article
Azam, A. S., Tsang, Y., Thirlwall, J., Kimani, P. K., Sah, S., Gopalakrishnan, K., …Snead, D. R. J. (2024). Digital pathology for reporting histopathology samples, including cancer screening samples – definitive evidence from a multisite study. Histopathology, 84(5), 847-862. https://doi.org/10.1111/his.15129

Aims: To conduct a definitive multicentre comparison of digital pathology (DP) with light microscopy (LM) for reporting histopathology slides including breast and bowel cancer screening samples. Methods: A total of 2024 cases (608 breast, 607 GI, 6... Read More about Digital pathology for reporting histopathology samples, including cancer screening samples – definitive evidence from a multisite study.