Modifying the m6A brain methylome by ALKBH5-mediated demethylation: a new contender for synaptic tagging

Martinez De La Cruz, Braulio; Markus, Robert; Malla, Sunir; Haig, Maria Isabel; Gell, Chris; Sang, Fei; Bellows, Eleanor; Sherif, Mahmoud Awad; McLean, Denise; Lourdusamy, Anbarasu; Self, Tim; Bodi, Zsuzsanna; Smith, Stuart; Fay, Michael; Macdonald, Ian A.; Fray, Rupert; Knight, Helen Miranda

doi:10.1038/s41380-021-01282-z

All Outputs (3)

Comparative transcriptome reprogramming in oak galls containing asexual or sexual generations of gall wasps (2024)
Journal Article

Oak gall wasps have evolved strategies to manipulate the developmental pathways of their host to induce gall formation. This provides shelter and nutrients for the developing larva. Galls are entirely host tissue; however, the initiation, development... Read More about Comparative transcriptome reprogramming in oak galls containing asexual or sexual generations of gall wasps.

The importance of m6A topology in chicken embryo mRNA: a precise mapping of m6A at the conserved chicken β-actin zipcode (2023)
Journal Article

N6-methyladenosine (m6A) in mRNA regulates almost every stage in the mRNA life cycle, and the development of methodologies for the high-throughput detection of methylated sites in mRNA using m6A-specific methylated RNA immunoprecipitation with next-g... Read More about The importance of m6A topology in chicken embryo mRNA: a precise mapping of m6A at the conserved chicken β-actin zipcode.

Modifying the m6A brain methylome by ALKBH5-mediated demethylation: a new contender for synaptic tagging (2021)
Journal Article

Synaptic plasticity processes, which underlie learning and memory formation, require RNA to be translated local to synapses. The synaptic tagging hypothesis has previously been proposed to explain how mRNAs are available at specific activated synapse... Read More about Modifying the m6A brain methylome by ALKBH5-mediated demethylation: a new contender for synaptic tagging.