Nucleotide exchange factor Rab3GEP requires DENN and non-DENN elements for activation and targeting of Rab27a
(2019)
Journal Article
Sanzà, P., Evans, R. D., Briggs, D. A., Cantero, M., Montoliu, L., Patel, S., …Hume, A. N. (2019). Nucleotide exchange factor Rab3GEP requires DENN and non-DENN elements for activation and targeting of Rab27a. Journal of Cell Science, 132(9), 1-8. https://doi.org/10.1242/jcs.212035
Rab GTPases are compartment-specific molecular switches that regulate intracellular vesicular transport in eukaryotes. GDP/GTP exchange factors (GEFs) control Rab activation, and current models propose that localised and regulated GEF activity is imp... Read More about Nucleotide exchange factor Rab3GEP requires DENN and non-DENN elements for activation and targeting of Rab27a.