PIP5K1α is Required for Promoting Tumor Progression in Castration-Resistant Prostate Cancer

Wang, Tianyan; Sarwar, Martuza; Whitchurch, Jonathan B.; Collins, Hilary M.; Green, Tami; Semenas, Julius; Ali, Amjad; Roberts, Christopher J.; Morris, Ryan D.; Hubert, Madlen; Chen, Sa; El-Schich, Zahra; Wingren, Anette G.; Grundström, Thomas; Lundmark, Richard; Mongan, Nigel P.; Gunhaga, Lena; Heery, David M.; Persson, Jenny L.

doi:10.3389/fcell.2022.798590

All Outputs (2)

Decision letter: Human WDR5 promotes breast cancer growth and metastasis via KMT2-independent translation regulation (2022)
Other
(2022). Decision letter: Human WDR5 promotes breast cancer growth and metastasis via KMT2-independent translation regulation

PIP5K1α is Required for Promoting Tumor Progression in Castration-Resistant Prostate Cancer (2022)
Journal Article
Wang, T., Sarwar, M., Whitchurch, J. B., Collins, H. M., Green, T., Semenas, J., …Persson, J. L. (2022). PIP5K1α is Required for Promoting Tumor Progression in Castration-Resistant Prostate Cancer. Frontiers in Cell and Developmental Biology, 10, Article 798590. https://doi.org/10.3389/fcell.2022.798590

PIP5K1α has emerged as a promising drug target for the treatment of castration-resistant prostate cancer (CRPC), as it acts upstream of the PI3K/AKT signaling pathway to promote prostate cancer (PCa) growth, survival and invasion. However, little is... Read More about PIP5K1α is Required for Promoting Tumor Progression in Castration-Resistant Prostate Cancer.