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Theoretical evaluation of wall teichoic acids in the cavitation-mediated pores formation in Gram-positive bacteria subjected to an electric field (2014)
Journal Article
Rauch, C., & Leigh, J. A. (in press). Theoretical evaluation of wall teichoic acids in the cavitation-mediated pores formation in Gram-positive bacteria subjected to an electric field. BBA - General Subjects, 1850(4), https://doi.org/10.1016/j.bbagen.2014.12.004

Background: Electroporation is a method of choice to transform living cells. The ability of electroporation to transfer small or large chemicals across the lipid bilayer membrane of eukaryotic cells or Gram-negative bacteria relies on the formation o... Read More about Theoretical evaluation of wall teichoic acids in the cavitation-mediated pores formation in Gram-positive bacteria subjected to an electric field.

Physics of nail conditions: why do ingrown nails always happen in the big toes? (2014)
Journal Article
Rauch, C., & Cherkaoui-Rbati, M. (2014). Physics of nail conditions: why do ingrown nails always happen in the big toes?. Physical Biology, 11(6), Article 066004. https://doi.org/10.1088/1478-3975/11/6/066004

Although surgical treatment of nail conditions can be traced back centuries to the writings of Paul Aegineta (625–690 AC), little is known about the physical laws governing nail growth. Such a poor understanding together with the increasing number of... Read More about Physics of nail conditions: why do ingrown nails always happen in the big toes?.

Mechanism of mucosal permeability enhancement of CriticalSorb® (Solutol® HS15) investigated in vitro in cell cultures (2014)
Journal Article

Purpose: CriticalSorb™, with the principal component Solutol® HS15, is a novel mucosal drug delivery system demonstrated to improve the bioavailability of selected biotherapeutics. The intention of this study is to elucidate mechanism(s) responsible... Read More about Mechanism of mucosal permeability enhancement of CriticalSorb® (Solutol® HS15) investigated in vitro in cell cultures.

The role of proton dynamics in the development and maintenance of multidrug resistance in cancer (2013)
Journal Article
Daniel, C., Bell, C., Burton, C., Harguindey, S., Reshkinc, S. J., & Rauch, C. (2013). The role of proton dynamics in the development and maintenance of multidrug resistance in cancer. Biochimica et Biophysica Acta (BBA) - Molecular and Cell Biology of Lipids, 1832(5), https://doi.org/10.1016/j.bbadis.2013.01.020

With a projected 382.4 per 100,000 people expected to suffer from some form of malignant neoplasm in 2015, improving treatment is an essential focus of cancer research today. Multi-drug resistance (MDR) is the leading cause of chemotherapeutic failur... Read More about The role of proton dynamics in the development and maintenance of multidrug resistance in cancer.

Membranes, molecules and biophysics: enhancing monocyte derived dendritic cell (MDDC) immunogenicity for improved anti-cancer therapy (2013)
Journal Article
Rauch, C., Ibrahim, H., & Foster, N. (2013). Membranes, molecules and biophysics: enhancing monocyte derived dendritic cell (MDDC) immunogenicity for improved anti-cancer therapy. Journal of cancer therapeutics & research, 2, Article 20. https://doi.org/10.7243/2049-7962-2-20

Despite great medical advancement in the treatment of cancer, cancer remains a disease of global significance. Chemotherapeutics can be very expensive and drain medical resources at a national level and in some cases the cost of treatment is so great... Read More about Membranes, molecules and biophysics: enhancing monocyte derived dendritic cell (MDDC) immunogenicity for improved anti-cancer therapy.