DEAD-box helicase eIF4A2 inhibits CNOT7 deadenylation activity

Meijer, Hedda A.; Schmidt, Tobias; Gillen, Sarah L.; Langlais, Claudia; Jukes-Jones, Rebekah; de Moor, Cornelia H.; Cain, Kelvin; Wilczynska, Ania; Bushell, Martin

doi:10.1093/nar/gkz509

All Outputs (1)

DEAD-box helicase eIF4A2 inhibits CNOT7 deadenylation activity (2019)
Journal Article
Meijer, H. A., Schmidt, T., Gillen, S. L., Langlais, C., Jukes-Jones, R., de Moor, C. H., …Bushell, M. (2019). DEAD-box helicase eIF4A2 inhibits CNOT7 deadenylation activity. Nucleic Acids Research, 47(15), 8224-8238. https://doi.org/10.1093/nar/gkz509

The CCR4–NOT complex plays an important role in the translational repression and deadenylation of mRNAs. However, little is known about the specific roles of interacting factors. We demonstrate that the DEAD-box helicases eIF4A2 and DDX6 interact dir... Read More about DEAD-box helicase eIF4A2 inhibits CNOT7 deadenylation activity.