All Outputs (59)

A validation study of the identification of haemophagocytic lymphohistiocytosis in England using population-based health data (2021)
Preprint / Working Paper
Bishton, M., Stilwell, P., Card, T. R., Lanyon, P., Ban, L., Elliss-Brookes, L., …Bythell, M. A validation study of the identification of haemophagocytic lymphohistiocytosis in England using population-based health data

We assessed the validity of coded health care data to identify cases of haemophagocytic lymphohistiocytosis (HLH). Hospital Episode Statistics (HES) identified 127 cases within five hospital Trusts 2013-2018 using ICD-10 codes D76.1, D76.2 and D76.3.... Read More about A validation study of the identification of haemophagocytic lymphohistiocytosis in England using population-based health data.

Outcomes after non-operative management of perforated diverticular disease: a population-based cohort study (2021)
Journal Article
Adiamah, A., Ban, L., Otete, H., Crooks, C. J., West, J., & Humes, D. J. (2021). Outcomes after non-operative management of perforated diverticular disease: a population-based cohort study. BJS Open, 5(2), Article zraa073. https://doi.org/10.1093/bjsopen/zraa073

BACKGROUND: The management of perforated diverticular disease has changed in the past 10 years with a move towards less surgical intervention. This population-based cohort study aimed to define the risk of death and readmission following non-operativ... Read More about Outcomes after non-operative management of perforated diverticular disease: a population-based cohort study.

COVID-19-associated hyperinflammation and escalation of patient care: a retrospective longitudinal cohort study (2020)
Journal Article
Manson, J. J., Crooks, C., Naja, M., Ledlie, A., Goulden, B., Liddle, T., …Tattersall, R. (2020). COVID-19-associated hyperinflammation and escalation of patient care: a retrospective longitudinal cohort study. The Lancet Rheumatology, 2(10), e594-e602. https://doi.org/10.1016/S2665-9913%2820%2930275-7

Background: A subset of patients with severe COVID-19 develop a hyperinflammatory syndrome, which might contribute to morbidity and mortality. This study explores a specific phenotype of COVID-19-associated hyperinflammation (COV-HI), and its associa... Read More about COVID-19-associated hyperinflammation and escalation of patient care: a retrospective longitudinal cohort study.

Supervised Bayesian statistical learning to identify prognostic risk factor patterns from population data (2020)
Book Chapter
Crooks, C. J. (2020). Supervised Bayesian statistical learning to identify prognostic risk factor patterns from population data. In L. B. Pape-Haugaard, C. Lovis, I. Cort Madsen, P. Weber, P. Hostrup Nielsen, & P. Scott (Eds.), Digital personalized health and medicine: Proceedings of MIE 2020 (422-426). IOS Press. https://doi.org/10.3233/SHTI200195

Current methods for building risk models assume averaged uniform effects across populations. They use weighted sums of individual risk factors from regression models with only a few interactions, such as age. This does not allow risk factor effects t... Read More about Supervised Bayesian statistical learning to identify prognostic risk factor patterns from population data.

Incidence, prevalence and mortality of autoimmune hepatitis in England 1997-2015. A population-based cohort study (2020)
Journal Article
Grønbæk, L., Otete, H., Ban, L., Crooks, C., Card, T., Jepsen, P., & West, J. (2020). Incidence, prevalence and mortality of autoimmune hepatitis in England 1997-2015. A population-based cohort study. Liver International, 40(7), 1634-1644. https://doi.org/10.1111/liv.14480

© 2020 John Wiley & Sons A/S. Published by John Wiley & Sons Ltd Background & Aims: There are few population-based studies of the incidence and mortality of autoimmune hepatitis. The burden of the disease and how it has changed over time have not... Read More about Incidence, prevalence and mortality of autoimmune hepatitis in England 1997-2015. A population-based cohort study.

A validation study of the CirCom comorbidity score in an English cirrhosis population using the Clinical Practice Research Datalink (2018)
Journal Article
Crooks, C. J., West, J., & Jepson, P. (2018). A validation study of the CirCom comorbidity score in an English cirrhosis population using the Clinical Practice Research Datalink. Clinical Epidemiology, 2018:10, https://doi.org/10.2147/CLEP.S147535

Purpose: The CirCom score has been developed from Danish data as a specific measure of comorbidity for cirrhosis to predict all-cause mortality. We compared its performance with the Charlson Comorbidity Index (CCI) in an English cirrhosis population.... Read More about A validation study of the CirCom comorbidity score in an English cirrhosis population using the Clinical Practice Research Datalink.

The risk of Clostridium difficile infection in patients with pernicious anaemia: a retrospective cohort study using primary care database. (2017)
Journal Article
Othman, F., Crooks, C. J., & Card, T. R. (in press). The risk of Clostridium difficile infection in patients with pernicious anaemia: a retrospective cohort study using primary care database. United European Gastroenterology Journal, https://doi.org/10.1177/2050640617695697

Background: Studies have found an association between proton pump inhibitor (PPI) use and Clostridium difficile infection. The purpose of this study was to determine whether the mechanism by which PPIs induce an increased risk of C. difficile infecti... Read More about The risk of Clostridium difficile infection in patients with pernicious anaemia: a retrospective cohort study using primary care database..

Community acquired pneumonia incidence before and after proton pump inhibitor prescription: population based study (2016)
Journal Article
Othman, F., Crooks, C. J., & Card, T. R. (2016). Community acquired pneumonia incidence before and after proton pump inhibitor prescription: population based study. BMJ, 355, Article i5813. https://doi.org/10.1136/bmj.i5813

Objective To examine the risk of community acquired pneumonia before and after prescription of proton pump inhibitor (PPI) and assess whether unmeasured confounding explains this association. Design Cohort study and self controlled case series. S... Read More about Community acquired pneumonia incidence before and after proton pump inhibitor prescription: population based study.

The use of a bayesian hierarchy to develop and validate a co-morbidity score to predict mortality for linked primary and secondary care data from the NHS in England (2016)
Journal Article
Crooks, C. J., Card, T. R., & West, J. (2016). The use of a bayesian hierarchy to develop and validate a co-morbidity score to predict mortality for linked primary and secondary care data from the NHS in England. PLoS ONE, 11(10), 1-16. https://doi.org/10.1371/journal.pone.0165507

Background: We have assessed whether the linkage between routine primary and secondary care records provided an opportunity to develop an improved population based co-morbidity score with the combined information on co-morbidities from both health ca... Read More about The use of a bayesian hierarchy to develop and validate a co-morbidity score to predict mortality for linked primary and secondary care data from the NHS in England.

Proton pump inhibitor prescribing patterns in the UK: a primary care database study (2016)
Journal Article
Othman, F., Card, T. R., & Crooks, C. J. (2016). Proton pump inhibitor prescribing patterns in the UK: a primary care database study. Pharmacoepidemiology and Drug Safety, 25(9), 1079-1087. https://doi.org/10.1002/pds.4043

Purpose: To determine the prevalence and pattern of proton pump inhibitor (PPI) prescription and the practices employed to reduce PPI use in the UK general population. Methods: The UK's Clinical Practice Research Database was used to identify indi... Read More about Proton pump inhibitor prescribing patterns in the UK: a primary care database study.

The risk of community-acquired pneumonia among 9803 patients with coeliac disease compared to the general population: a cohort study (2016)
Journal Article
Zingone, F., Abdul Sultan, A., Crooks, C. J., Tata, L. J., Ciacci, C., & West, J. (in press). The risk of community-acquired pneumonia among 9803 patients with coeliac disease compared to the general population: a cohort study. Alimentary Pharmacology and Therapeutics, 44(1), https://doi.org/10.1111/apt.13652

Background: Patients with coeliac disease are considered as individuals for whom pneumococcal vaccination is advocated. Aim: To quantify the risk of community-acquired pneumonia among patients with coeliac disease, assessing whether vaccination ag... Read More about The risk of community-acquired pneumonia among 9803 patients with coeliac disease compared to the general population: a cohort study.

Causes of death in people with coeliac disease in England compared with the general population: a competing risk analysis (2015)
Journal Article
Abdul Sultan, A., Crooks, C. J., Card, T. R., Tata, L. J., Fleming, K. M., & West, J. (2015). Causes of death in people with coeliac disease in England compared with the general population: a competing risk analysis. Gut, 64(8), https://doi.org/10.1136/gutjnl-2014-308285

INTRODUCTION: Quantifying excess cause-specific mortality among people with coeliac disease (CD) compared with the general population accounting for competing risks will allow accurate information to be given on risk of death from specific causes.... Read More about Causes of death in people with coeliac disease in England compared with the general population: a competing risk analysis.

A comparison of the recording of comorbidity in primary and secondary care by using the Charlson Index to predict short-term and long-term survival in a routine linked data cohort (2015)
Journal Article
Crooks, C. J., West, J., & Card, T. R. (2015). A comparison of the recording of comorbidity in primary and secondary care by using the Charlson Index to predict short-term and long-term survival in a routine linked data cohort. BMJ Open, 5(6), Article e007974. https://doi.org/10.1136/bmjopen-2015-007974

OBJECTIVE: Hospital admission records provide snapshots of clinical histories for a subset of the population admitted to hospital. In contrast, primary care records provide continuous clinical histories for complete populations, but might lack detail... Read More about A comparison of the recording of comorbidity in primary and secondary care by using the Charlson Index to predict short-term and long-term survival in a routine linked data cohort.

Socioeconomic variation in the incidence of childhood coeliac disease in the UK (2015)
Journal Article
Zingone, F., West, J., Crooks, C. J., Fleming, K. M., Card, T. R., Ciacci,, C., & Tata, L. J. (2015). Socioeconomic variation in the incidence of childhood coeliac disease in the UK. Archives of Disease in Childhood, 100(5), https://doi.org/10.1136/archdischild-2014-307105

BACKGROUND: Serological studies indicate that evidence of coeliac disease (CD) exists in about 1% of all children, but we lack estimates of current diagnostic patterns among children and how they vary by socioeconomic group. METHODS: We identifie... Read More about Socioeconomic variation in the incidence of childhood coeliac disease in the UK.

Pregnancy complications and adverse birth outcomes among women with celiac disease: a population-based study from England (2014)
Journal Article
Abdul Sultan, A., Tata, L. J., Fleming, K. M., Crooks, C. J., Ludvigsson, J. F., Dhalwani, N. N., …West, J. (in press). Pregnancy complications and adverse birth outcomes among women with celiac disease: a population-based study from England. American Journal of Gastroenterology, 109(10), https://doi.org/10.1038/ajg.2014.196

OBJECTIVES: Evidence-based information about adverse birth outcomes and pregnancy complications is crucial when counseling women with celiac disease (CD); however, limited population-based data on such risks exist. We estimated these for pregnant wom... Read More about Pregnancy complications and adverse birth outcomes among women with celiac disease: a population-based study from England.

1 and 5 year survival estimates for people with cirrhosis of the liver in England, 1998–2009: a large population study (2014)
Journal Article
Ratib, S., Fleming, K. M., Crooks, C. J., Aithal, G. P., & West, J. (2014). 1 and 5 year survival estimates for people with cirrhosis of the liver in England, 1998–2009: a large population study. Journal of Hepatology, 60(2), https://doi.org/10.1016/j.jhep.2013.09.027

BACKGROUND & AIMS: Large, population-based studies that have included the full spectrum of cirrhosis estimating survival, taking into account time-at-risk are lacking. We aimed to report 1- and 5-year average survival rates for people with cirrhosis... Read More about 1 and 5 year survival estimates for people with cirrhosis of the liver in England, 1998–2009: a large population study.

Occurrence of liver cirrhosis in England, a cohort study, 1998-2009: a comparison with cancer (2014)
Journal Article
Ratib, S., West, J., Crooks, C. J., & Fleming, K. M. (2014). Occurrence of liver cirrhosis in England, a cohort study, 1998-2009: a comparison with cancer. American Journal of Gastroenterology, 109(2), https://doi.org/10.1038/ajg.2013.405

OBJECTIVES: There is no routine registration of the occurrence of newly diagnosed cases of cirrhosis in the United Kingdom. This study seeks to determine precise estimates and trends of the incidence of cirrhosis in England, and directly compare the... Read More about Occurrence of liver cirrhosis in England, a cohort study, 1998-2009: a comparison with cancer.

Comorbidities affect risk of nonvariceal upper gastrointestinal bleeding (2013)
Journal Article
Crooks, C. J., West, J., & Card, T. R. (2013). Comorbidities affect risk of nonvariceal upper gastrointestinal bleeding. Gastroenterology, 144(7), Article 1384-1393.e2. https://doi.org/10.1053/j.gastro.2013.02.040

Background & Aims The incidence of upper gastrointestinal bleeding (GIB) has not been reduced despite the decreasing incidence of peptic ulcers, strategies to eradicate Helicobacter pylori infection, and prophylaxis against ulceration from nonsteroi... Read More about Comorbidities affect risk of nonvariceal upper gastrointestinal bleeding.

Excess long-term mortality following non-variceal upper gastrointestinal bleeding: a population-based cohort study (2013)
Journal Article
Crooks, C. J., Card, T. R., & West, J. (2013). Excess long-term mortality following non-variceal upper gastrointestinal bleeding: a population-based cohort study. PLoS Medicine, 10(4), Article e1001437. https://doi.org/10.1371/journal.pmed.1001437

Background It is unclear whether an upper gastrointestinal bleed is an isolated gastrointestinal event or an indicator of a deterioration in a patient's overall health status. Therefore, we investigated the excess causes of death in individuals afte... Read More about Excess long-term mortality following non-variceal upper gastrointestinal bleeding: a population-based cohort study.