All Outputs (6)

Neural correlates of hyperalgesia in the monosodium iodoacetate model of osteoarthritis pain (2016)
Journal Article
Abaei, M., Sagar, D. R., Stockley, E. G., Spicer, C. H., Prior, M., Chapman, V., & Auer, D. P. (in press). Neural correlates of hyperalgesia in the monosodium iodoacetate model of osteoarthritis pain. Molecular Pain, 12, https://doi.org/10.1177/1744806916642445

Background: The mechanisms driving osteoarthritic pain remain poorly understood, but there is increasing evidence for a role of the central nervous system in the chronification of pain.We used functional magnetic resonance imaging to investigate the... Read More about Neural correlates of hyperalgesia in the monosodium iodoacetate model of osteoarthritis pain.

Contribution of serotonin and dopamine to changes in core body temperature and locomotor activity in rats following repeated administration of mephedrone (2015)
Journal Article
Shortall, S. E., Spicer, C. H., Ebling, F. J., Green, A. R., Fone, K. C., & King, M. V. (2016). Contribution of serotonin and dopamine to changes in core body temperature and locomotor activity in rats following repeated administration of mephedrone. Addiction Biology, 21(6), 1127-1139. https://doi.org/10.1111/adb.12283

© 2015 Society for the Study of Addiction The psychoactive effects of mephedrone are commonly compared with those of 3,4-methylenedioxymethamphetamine, but because of a shorter duration of action, users often employ repeated administration to mainta... Read More about Contribution of serotonin and dopamine to changes in core body temperature and locomotor activity in rats following repeated administration of mephedrone.

Reduced dopamine function within the medial shell of the nucleus accumbens enhances latent inhibition (2011)
Journal Article
Nelson, A. J., Thur, K. E., Horsley, R., Spicer, C., Marsden, C., & Cassaday, H. J. (2011). Reduced dopamine function within the medial shell of the nucleus accumbens enhances latent inhibition. Pharmacology Biochemistry and Behavior, 98(1), https://doi.org/10.1016/j.pbb.2010.11.025

Latent inhibition (LI) manifests as poorer conditioning to a CS that has previously been presented without consequence. There is some evidence that LI can be potentiated by reduced mesoaccumbal dopamine (DA) function but the locus within the nucleus... Read More about Reduced dopamine function within the medial shell of the nucleus accumbens enhances latent inhibition.

Early life programming of fear conditioning and extinction in adult male rats (2009)
Journal Article
Stevenson, C. W., Spicer, C. H., Mason, R., & Marsden, C. A. (2009). Early life programming of fear conditioning and extinction in adult male rats. Behavioural Brain Research, 205(2), 505-510. https://doi.org/10.1016/j.bbr.2009.08.005

The early rearing environment programs corticolimbic function and neuroendocrine stress reactivity in adulthood. Although early environmental programming of innate fear has been previously examined, its impact on fear learning and memory later in lif... Read More about Early life programming of fear conditioning and extinction in adult male rats.

Neonatal maternal separation alters reward-related ultrasonic vocalizations in rat dams (2009)
Journal Article
Stevenson, C. W., Goodwin, P. E., Tunstall, B., Spicer, C. H., Marsden, C. A., & Mason, R. (2009). Neonatal maternal separation alters reward-related ultrasonic vocalizations in rat dams. Behavioural Brain Research, 200(1), 232-236. https://doi.org/10.1016/j.bbr.2009.01.035

We examined the effects of brief or long durations of repeated maternal separation (MS) on ultrasonic vocalizations (USVs) in rat dams. 50-kHz USVs putatively identified as maternal in origin were emitted only immediately after pups were returned fol... Read More about Neonatal maternal separation alters reward-related ultrasonic vocalizations in rat dams.

Early life programming of innate fear and fear learning in adult female rats (2008)
Journal Article
Stevenson, C. W., Meredith, J. P., Spicer, C. H., Mason, R., & Marsden, C. A. (2009). Early life programming of innate fear and fear learning in adult female rats. Behavioural Brain Research, 198(1), 51-57. https://doi.org/10.1016/j.bbr.2008.10.021

The early rearing environment can impact on emotional reactivity and learning later in life. In this study the effects of neonatal maternal separation (MS) on innate fear and fear learning were assessed in the adult female rat. Pups were subjected to... Read More about Early life programming of innate fear and fear learning in adult female rats.