All Outputs (92)

Analysis of human immunodeficiency virus type 1 env and gag sequence variants derived from a mother and two vertically infected children provides evidence for the transmission of multiple sequence variants (1998)
Journal Article
Wade, C. M., Lobidel, D., & Leigh Brown, A. J. (1998). Analysis of human immunodeficiency virus type 1 env and gag sequence variants derived from a mother and two vertically infected children provides evidence for the transmission of multiple sequence variants. Journal of General Virology, 79(5), 1055-1068. https://doi.org/10.1099/0022-1317-79-5-1055

In order to investigate the transmission of human immunodeficiency virus type 1 (HIV-1) from mother-to-child we have examined serial plasma RNA samples obtained from a mother over an eight year period spanning four pregnancies. Child 1 and 2 (born Ja... Read More about Analysis of human immunodeficiency virus type 1 env and gag sequence variants derived from a mother and two vertically infected children provides evidence for the transmission of multiple sequence variants.

Analysis of HIV-1 and foraminiferal molecular evolution (1997)
Thesis
Wade, C. (1997). Analysis of HIV-1 and foraminiferal molecular evolution. (Dissertation). University of Edinburgh. Retrieved from https://nottingham-repository.worktribe.com/output/34111093

This thesis presents work examining aspects of both HIV- 1 and foraminiferal evolution. The thesis is set out accordingly into two sections, each of which contains an introduction with individual chapters presented as a series of papers. In section... Read More about Analysis of HIV-1 and foraminiferal molecular evolution.

The molecular epidemiology of human immunodeficiency virus type 1 in six cities in Britain and Ireland (1997)
Journal Article
Brown, A. J., Lobidel, D., Wade, C. M., Rebus, S., Phillips, A. N., Brettle, R. P., …Peutherer, J. F. (1997). The molecular epidemiology of human immunodeficiency virus type 1 in six cities in Britain and Ireland. Virology, 235(1), 166-177. https://doi.org/10.1006/viro.1997.8656

We have sequenced the p17 coding regions of the gag gene from 211 patients infected either through injecting drug use (IDU) or by sexual intercourse between men from six cities in Scotland, N. England, N. Ireland, and the Republic of Ireland. All seq... Read More about The molecular epidemiology of human immunodeficiency virus type 1 in six cities in Britain and Ireland.

Evolution of human immunodeficiency virus type 1 in perinatally infected infants with rapid and slow progression to disease (1997)
Journal Article
Salvatori, F., Masiero, S., Giaquinto, C., Wade, C. M., Leigh Brown, A. J., Chieco-Bianchi, L., & De Rossi, A. (1997). Evolution of human immunodeficiency virus type 1 in perinatally infected infants with rapid and slow progression to disease. Journal of Virology, 71(6), 4694-4706. https://doi.org/10.1128/jvi.71.6.4694-4706.1997

We addressed the relationship between the origin and evolution of human immunodeficiency virus type 1 (HIV-1) variants and disease outcome in perinatally infected infants by studying the V3 regions of viral variants in samples obtained from five tran... Read More about Evolution of human immunodeficiency virus type 1 in perinatally infected infants with rapid and slow progression to disease.

Planktic foraminiferal molecular evolution and their polyphyletic origins from benthic taxa (1997)
Journal Article
Darling, K. F., Wade, C. M., Kroon, D., & Brown, A. J. (1997). Planktic foraminiferal molecular evolution and their polyphyletic origins from benthic taxa. Marine Micropaleontology, 30(4), 251-266. https://doi.org/10.1016/S0377-8398%2896%2900057-6

Phylogenetic analyses based on partial sequences of the small subunit (SSU) ribosomal (r) RNA gene have shown that the planktic and benthic foraminifera form a distinct monophyletic group within the eukaryotes. In order to determine the evolutionary... Read More about Planktic foraminiferal molecular evolution and their polyphyletic origins from benthic taxa.

The isolation and amplification of the 18S ribosomal RNA gene from planktonic foraminifers using gametogenic specimens (1996)
Book Chapter
Darling, K., Kroon, D., Wade, C., & Leigh Brown, A. (1996). The isolation and amplification of the 18S ribosomal RNA gene from planktonic foraminifers using gametogenic specimens. In A. Moguilevsky, & R. Whatley (Eds.), Microfossils and oceanic environments. University of Wales, Aberystwyth Press

Reading the history of the oceans in plankton DNA (1996)
Journal Article
Darling, K., Kroon, D., Wade, C., & Brown, A. (1996). Reading the history of the oceans in plankton DNA. NERC News, 16-17

Molecular epidemiology of HIV in Scotland and Ireland (1996)
Book Chapter
Lobidel, D., Wade, C., Rebus, S., & Leigh Brown, A. (1996). Molecular epidemiology of HIV in Scotland and Ireland. In Program and abstracts of the 3rd Conference on Retroviruses and Opportunistic Infections: Sheraton Washington Hotel, January 28-February 2 [i.e. 1], 1996, Washington, DC. Infectious Diseases Society of America for the Foundation for Retrovirology and Human Health

Early evolutionary origin of the planktic foraminifera inferred from small subunit rDNA sequence comparisons (1996)
Journal Article
Wade, C. M., Darling, K. F., Kroon, D., & Leigh Brown, A. J. (1996). Early evolutionary origin of the planktic foraminifera inferred from small subunit rDNA sequence comparisons. Journal of Molecular Evolution, 43(6), 672-677. https://doi.org/10.1007/BF02202115

Phylogenetic analysis of five partial planktic foraminiferal small subunit (SSU) ribosomal (r) DNA sequences with representatives of a diverse range of eukaryote, archaebacterial, and eubacterial taxa has revealed that the evolutionary origin of the... Read More about Early evolutionary origin of the planktic foraminifera inferred from small subunit rDNA sequence comparisons.

Molecular phylogeny of the planktic foraminifera (1996)
Journal Article
Darling, K. F., Kroon, D., Wade, C. M., & Leigh Brown, A. J. (1996). Molecular phylogeny of the planktic foraminifera. Journal of Foraminiferal Research, 26(4), 324-330. https://doi.org/10.2113/gsjfr.26.4.324

Planktic foraminifers are an important group of marine Zooplankton whose fossil record has been used extensively to reconstruct past climatic and oceanographic changes. Knowledge of the molecular phylogenetics of the planktic foraminifera will allow... Read More about Molecular phylogeny of the planktic foraminifera.

Protecting HIV databases (1995)
Journal Article
Briant, L., Puel, J., Wade, C. M., Brown, A. J., & Guyader, M. (1995). Protecting HIV databases. Nature, 378(6554), 243-244. https://doi.org/10.1038/378243a0

We fully agree with Korber et al. concerning the importance of the issue of sample contamination. We had, in fact, carried out a more detailed analysis than theirs which was indeed considered as part of the review process of our paper. Sample timing... Read More about Protecting HIV databases.

Analysis of envelope sequence variants suggests multiple mechanisms of mother-to-child transmission of human immunodeficiency virus type 1 (1995)
Journal Article
Briant, L., Wade, C. M., Puel, J., Leigh Brown, A. J., & Guyader, M. (1995). Analysis of envelope sequence variants suggests multiple mechanisms of mother-to-child transmission of human immunodeficiency virus type 1. Journal of Virology, 69(6), 3778-3788. https://doi.org/10.1128/jvi.69.6.3778-3788.1995

In order to elucidate the molecular mechanisms involved in human immunodeficiency virus type 1 (HIV-1) mother-to-child transmission, we have analyzed the genetic variation within the V3 hypervariable domain and flanking regions of the HIV-1 envelope... Read More about Analysis of envelope sequence variants suggests multiple mechanisms of mother-to-child transmission of human immunodeficiency virus type 1.