All Outputs (2)

Sorting of GPI-anchored proteins at the trypanosome surface is independent of GPI insertion signals (2024)
Journal Article
Miller, T. H., Schiessler, S., Rogerson, E. M., & Gadelha, C. (2024). Sorting of GPI-anchored proteins at the trypanosome surface is independent of GPI insertion signals. The Cell Surface, 12, Article 100131. https://doi.org/10.1016/j.tcsw.2024.100131

The segregation of glycosylphosphatidylinositol-anchored proteins (GPI-APs) to distinct domains on the plasma membrane of eukaryotic cells is important for their correct cellular function, but the mechanisms by which GPI-APs are sorted are yet to be... Read More about Sorting of GPI-anchored proteins at the trypanosome surface is independent of GPI insertion signals.

A conserved trypanosomatid differentiation regulator controls substrate attachment and morphological development in Trypanosoma congolense (2024)
Journal Article
Silvester, E., Szoor, B., Ivens, A., Awuah-Mensah, G., Gadelha, C., Wickstead, B., & Matthews, K. R. (2024). A conserved trypanosomatid differentiation regulator controls substrate attachment and morphological development in Trypanosoma congolense. PLoS Pathogens, 20(2), Article e1011889. https://doi.org/10.1371/journal.ppat.1011889

Trypanosomatid parasites undergo developmental regulation to adapt to the different environments encountered during their life cycle. In Trypanosoma brucei, a genome wide selectional screen previously identified a regulator of the protein family ESAG... Read More about A conserved trypanosomatid differentiation regulator controls substrate attachment and morphological development in Trypanosoma congolense.