All Outputs (4)

Randomised controlled trial of bariatric surgery versus a community weight loss programme for the sustained treatment of idiopathic intracranial hypertension: the Idiopathic Intracranial Hypertension Weight Trial (IIH:WT) protocol (2017)
Journal Article
Ottridge, R., Mollan, S. P., Botfield, H., Frew, E., Ives, N. J., Matthews, T., …Sinclair, A. J. (2017). Randomised controlled trial of bariatric surgery versus a community weight loss programme for the sustained treatment of idiopathic intracranial hypertension: the Idiopathic Intracranial Hypertension Weight Trial (IIH:WT) protocol. BMJ Open, 7(9), 1-8. https://doi.org/10.1136/bmjopen-2017-017426

Introduction: Effective treatments are lacking for idiopathic intracranial hypertension (IIH), a condition characterised by raised intracranial pressure (ICP) and papilloedema, and found primarily in obese women. Weight loss and lowering body mass in... Read More about Randomised controlled trial of bariatric surgery versus a community weight loss programme for the sustained treatment of idiopathic intracranial hypertension: the Idiopathic Intracranial Hypertension Weight Trial (IIH:WT) protocol.

Assessing the Efficacy and Safety of an 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor (AZD4017) in the Idiopathic Intracranial Hypertension Drug Trial, IIH:DT: Clinical Methods and Design for a Phase II Randomized Controlled Trial (2017)
Journal Article
Markey, K. A., Ottridge, R., Mitchell, J. L., Rick, C., Woolley, R., Ives, N., …Sinclair, A. J. (2017). Assessing the Efficacy and Safety of an 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor (AZD4017) in the Idiopathic Intracranial Hypertension Drug Trial, IIH:DT: Clinical Methods and Design for a Phase II Randomized Controlled Trial. JMIR Research Protocols, 6(9), 1-10. https://doi.org/10.2196/resprot.7806

Background: Idiopathic intracranial hypertension (IIH) is a condition with few effective management options. So far, there have been no randomized controlled trials evaluating new treatments in IIH.

Objectives: The purpose of this paper is to outl... Read More about Assessing the Efficacy and Safety of an 11β-Hydroxysteroid Dehydrogenase Type 1 Inhibitor (AZD4017) in the Idiopathic Intracranial Hypertension Drug Trial, IIH:DT: Clinical Methods and Design for a Phase II Randomized Controlled Trial.

The PD COMM trial: a protocol for the process evaluation of a randomised trial assessing the effectiveness of two types of SLT for people with Parkinson’s disease (2017)
Journal Article
Masterson-Algar, P., Burton, C. R., Brady, M. C., Nicoll, A., Clarke, C. E., Rick, C., …Sackley, C. M. (2017). The PD COMM trial: a protocol for the process evaluation of a randomised trial assessing the effectiveness of two types of SLT for people with Parkinson’s disease. Trials, 18(1), 78. https://doi.org/10.1186/s13063-017-2130-1

Background
The PD COMM trial is a phase III multi-centre randomised controlled trial whose aim is to evaluate the effectiveness and cost-effectiveness of two approaches to speech and language therapy (SLT) compared with no SLT intervention (control)... Read More about The PD COMM trial: a protocol for the process evaluation of a randomised trial assessing the effectiveness of two types of SLT for people with Parkinson’s disease.

Coding accuracy for Parkinson's disease hospital admissions: implications for healthcare planning in the UK (2017)
Journal Article
Muzerengi, S., Rick, C., Begaj, I., Ives, N., Evison, F., Woolley, R., & Clarke, C. (2017). Coding accuracy for Parkinson's disease hospital admissions: implications for healthcare planning in the UK. Public Health, 146, 4-9. https://doi.org/10.1016/j.puhe.2016.12.024

Objectives
Hospital Episode Statistics data are used for healthcare planning and hospital reimbursements. Reliability of these data is dependent on the accuracy of individual hospitals reporting Secondary Uses Service (SUS) which includes hospitalis... Read More about Coding accuracy for Parkinson's disease hospital admissions: implications for healthcare planning in the UK.