A self‐assembled 3D model demonstrates how stiffness educates tumor cell phenotypes and therapy resistance in pancreatic cancer
(2024)
Journal Article
Liu, Y., Okesola, B. O., de la Peña, D. O., Li, W., Lin, M., Trabulo, S. M. D., …Pearce, O. M. (in press). A self‐assembled 3D model demonstrates how stiffness educates tumor cell phenotypes and therapy resistance in pancreatic cancer. Advanced Healthcare Materials, Article 2301941. https://doi.org/10.1002/adhm.202301941
Pancreatic ductal adenocarcinoma (PDAC) is characterized by a dense and stiff extracellular matrix (ECM) associated with tumor progression and therapy resistance. To further the understanding of how stiffening of the tumor microenvironment (TME) cont... Read More about A self‐assembled 3D model demonstrates how stiffness educates tumor cell phenotypes and therapy resistance in pancreatic cancer.