VEGFR2 promotes central endothelial activation and the spread of pain in inflammatory arthritis

Beazley-Long, Nicholas; Moss, Catherine Elizabeth; Ashby, William Robert; Bestall, Samuel Marcus; Almahasneh, Fatimah; Durrant, Alexandra Margaret; Benest, Andrew Vaughan; Blackley, Zoe; Hirashima, Masanori; Ballmer-Hofer, Kurt; Hulse, Richard Phillip; Bates, David Owen; Donaldson, Lucy Frances

doi:10.1016/j.bbi.2018.03.012

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VEGFR2 promotes central endothelial activation and the spread of pain in inflammatory arthritis (2018)
Journal Article
Beazley-Long, N., Moss, C. E., Ashby, W. R., Bestall, S. M., Almahasneh, F., Durrant, A. M., …Donaldson, L. F. (2018). VEGFR2 promotes central endothelial activation and the spread of pain in inflammatory arthritis. Brain, Behavior, and Immunity, 74, 49-67. https://doi.org/10.1016/j.bbi.2018.03.012

Chronic pain can develop in response to conditions such as inflammatory arthritis. The central mechanisms underlying the development and maintenance of chronic pain in humans are not well elucidated although there is evidence for a role of microglia... Read More about VEGFR2 promotes central endothelial activation and the spread of pain in inflammatory arthritis.